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Effect of differnce of mechanicalstress for muscle-tendon complex and enthesis

Research Project

Project/Area Number 24700545
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Rehabilitation science/Welfare engineering
Research InstitutionSaitama Prefectural University

Principal Investigator

KOKUBUN Takanori  埼玉県立大学, 保健医療福祉学部, 助教 (10616395)

Project Period (FY) 2012-04-01 – 2014-03-31
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2013: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2012: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Keywordsエンテーシス / メカニカルストレス / 遠心性収縮 / 炎症性サイトカイン / Enthesis / 血管新生因子
Research Abstract

In this research project, I investigated effect of different muscle contraction mode (Eccentric contraction and Concentric contraction) to the muscle tendon complex and tendon-bone interface (Enthesis) in animal model. The supraspinatus of shoulder joint and quadriceps (patellar tendon) of knee joint, clearly showed enthesis organs, were applied for histological and biochemical analysis. Consequently, supraspinatus of shoulder joint showed no significant difference of the effect of mechanical stress. On the other hand, patellar tendon of knee joint showed a tendency to early onset of inflamatlical reaction in postero-patellar fat-pad rather than other surrounding tissues.

Report

(3 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • Research Products

    (6 results)

All 2014 2013

All Journal Article (1 results) Presentation (5 results)

  • [Journal Article] ラット棘上筋腱の加齢変化と運動が血管内皮細胞増殖因子に与える影響2014

    • Author(s)
      村田健児,金村尚彦,国分貴徳,松本純一,藤野努,高柳清美
    • Journal Title

      12理学療法―臨床・研究・教育

      Volume: 第21巻 Pages: 12-15

    • NAID

      40019950032

    • Related Report
      2013 Final Research Report
  • [Presentation] Biochemical Changes affect immature patella tendon and Fat Pad after eccentric contraction2013

    • Author(s)
      Kokubun T, Kanemura N, Maejima H, Morita S, Takayanagi K
    • Organizer
      WCPT-AWP & ACPT Congress 2013
    • Place of Presentation
      Taichung,Taiwan
    • Year and Date
      2013-09-05
    • Related Report
      2013 Final Research Report
  • [Presentation] THE EFFECT OF EXERCISE ON THE VASCULAR ENDOTHELIAL GROWTH FACTOR IN THE SUPRASPINATUS TENDON2013

    • Author(s)
      Murata K, Kanemura N, Kokubun T, Matsumoto J, Fujino, T, Takayanagi K
    • Organizer
      WCPT-AWP & ACPT Congress 2013
    • Place of Presentation
      Taichung,Taiwan
    • Year and Date
      2013-09-05
    • Related Report
      2013 Final Research Report
  • [Presentation] 老齢ラットにおける運動が棘上筋腱骨付着部に及ぼす影響2013

    • Author(s)
      村田健児,金村尚彦,国分貴徳,藤野努,高柳清美
    • Organizer
      第48回日本理学療法学術大会
    • Place of Presentation
      名古屋市
    • Year and Date
      2013-05-24
    • Related Report
      2013 Final Research Report
  • [Presentation] Biochemical Changes affect immature patella tendon and Fat Pad after eccentric contraction2013

    • Author(s)
      Kokubun T, Kanemura N, Maejima H, Morita S, Takayanagi K
    • Organizer
      WCPT-AWP&ACPT Congress
    • Place of Presentation
      Taiwan
    • Related Report
      2013 Annual Research Report
  • [Presentation] Biochemical Changes that affect immature patella tendon and Fat Pad after eccentric contraction.2013

    • Author(s)
      Kokubun T1, Kanemura N, Maejima H, Morita S, Takayanagi K
    • Organizer
      WCPT-AWP & ACPT Congress 2013
    • Place of Presentation
      Taiwan
    • Related Report
      2012 Research-status Report

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Published: 2013-05-31   Modified: 2019-07-29  

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