| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2013: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2012: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Outline of Final Research Achievements |
The purpose of this study was to investigate whether metabolite accumulation per se enhances exercise-induced muscle hypertrophy. Young men completed an 8-wk resistance exercise program for knee extensor muscles. In order to accumulate metabolites after the exercise, blood flow restriction was applied after the exercise (post-exercise blood flow restriction, PEBFR). We found no additional effect of PEBFR on muscle hypertrophy. This result suggests the following possibilities: (1) no causal relationship would exist between metabolite accumulation and exercise-induced muscle hypertrophy, or (2) concomitant muscle contraction is essential for metabolite accumulation to cause additional hypertrophy. It should be noted that the result does not rule out the possibility of compensatory effects of metabolite accumulation on exercise-induced muscle hypertrophy, because this study used a moderate-load resistance exercise program which induced significant muscle hypertrophy independent of PEBFR.
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