Does long-term exercise reduce the nitration of organs caused by inflammation in rat infection model?
| Project/Area Number |
24700704
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Sports science
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| Research Institution | Hokuriku University (2013-2014)
Juntendo University (2012) |
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Principal Investigator |
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Keywords | タンパク質ニトロ化 / ニトロトリプトファン / ニトロ化ストレス / スポーツ生化学 |
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| Outline of Final Research Achievements |
Aim of the research is to know contribution of long-term spontaneous movements for the prevention of organ damage caused by the infection. In this research, it was able to obtain the knowledge in infection model animals and exercise model animals. In the infection model with lipopolysaccharide administration, the fate of the intensity and time variation of the response of nitrating and oxidative stress markers with the dose of lipopolysaccharide are different for each organ. The mice that do not have a moderate exercise, highly expression level of Mn- superoxide dismutase and large amount of oxygen consumption per body weight were observed.
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Report
(4 results)
Research Products
(16 results)
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[Journal Article] A Nutrition Survey of Atherosclerosis Patients to Study the Effects of Iron, Zinc, and Copper on Atherosclerosis2012
Author(s)
Naoki Shida, Yoko Tsuchiya, Fumiyuki Yamakura, Tatsuji Kano, Yuji Nakazato, Kazuko Takada, Sachio Kawai, Keiichi Ikeda, Yuko Amamiya, Shigeru Nakajima, Kazuhiko Machida, Hideaki Iwai
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Journal Title
Trace Nutrients Research
Volume: 29
Pages: 110-116
Related Report
Peer Reviewed
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