| Project/Area Number |
24700771
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Applied health science
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| Research Institution | Prefectural University of Kumamoto (2013)
National Institute of Health and Nutrition (2012) |
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Principal Investigator |
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| Project Period (FY) |
2012-04-01 – 2014-03-31
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2012: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Keywords | 脂肪肝 / 食事制限 / 有酸素運動 / 介入研究 / 糖代謝 / エネルギー代謝 / 内臓脂肪 / 糖尿病 |
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| Research Abstract |
The aim of the present study was to evaluate the effect of calorie restriction-induced weight loss, with or without aerobic exercise, on liver fat. Thirty-three adults were divided into calorie restriction (CR; n = 18) or CR and aerobic exercise (CR+Ex; n = 15) groups. Target energy intake was 25 kcal/kg of ideal body weight. The CR+Ex group had a targeted exercise time of 300 min/wk or more at lactate threshold intensity for 12 weeks. Reductions in body weight and visceral fat were not statistically different between groups. Liver fat decreased significantly in both groups, with no difference between groups. Calorie restriction-induced weight loss, with or without aerobic exercise, may provide an effective reduction in liver fat in adults. In addition, the results demonstrated that there were no additional benefits relating to liver fat and liver enzymes when aerobic exercise was prescribed together with calorie restriction (Yoshimura et al. J Obesity 2014).
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