The association between vitamin C intake and plasma concentration and physical function by vitamin C related DNA polymorphism
Project/Area Number |
24700860
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Multi-year Fund |
Research Field |
Eating habits, studies on eating habits
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Research Institution | Yokohama City University (2014-2015) Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology (2012-2013) |
Principal Investigator |
SAITO Kyoko 横浜市立大学, 医学部, 助教 (20507389)
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Project Period (FY) |
2012-04-01 – 2016-03-31
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Project Status |
Completed (Fiscal Year 2015)
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Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2013: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Fiscal Year 2012: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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Keywords | ビタミンC / 身体機能 / 高齢者 / 運動機能 / 血中ビタミンC濃度 / SVCT1 / SVCT2 / GSTs / 高齢女性 / ビタミン関連遺伝子多型 |
Outline of Final Research Achievements |
Recent studies suggest that vitamins AND minerals, which have antioxidant properties, enhances muscle strength and has prophylactic activity against bone fractures, osteoporosis, and decreases in physical performance. A cross-sectional study conducted in 2006 on community-dwelling elderly women suggested that high blood concentrations of vitamin C is associated with improved physical performance. This was done by conducting a follow-up survey in 2013 using the 2006 survey results as a baseline in order to provide a longitudinal analysis with a higher level of evidence. In community-dwelling women, the concentration of blood vitamin C related well to their physical performance. The association between baseline concentration of vitamin C and seven year change in physical function showed that maximal walking speed significantly increased.
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Report
(5 results)
Research Products
(8 results)
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[Journal Article] A significant relationship between plasma vitamin C concentration and physical performance among Japanese elderly women : Comparison in healthy Japanese subjects.2012
Author(s)
Saito K., Yokoyama T., Yoshida H., Kim H., Shimada H., Yoshida Y., Iwasa H., Shimizu Y., Kondo Y., Handa S., Maruyama N., Ishigami A. and Suzuki T.
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Journal Title
J. Gerontol. A Biol. Sci. Med. Sci.
Volume: 67(3)
Issue: 3
Pages: 295-301
DOI
Related Report
Peer Reviewed
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