Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2013: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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Research Abstract |
Fatty acid synthase is highly expressed in many kinds of human cancers. Cerulenin, a natural inhibitor of fatty acid synthase, induced apoptosis in human hetatic cancer cell line Huh7, Hep3B and HepG2. Next, we made orthotopic xenograft model of human liver cancer Huh7, Hep3B and HepG2.Treatment effect is now under review.Based on these studies, inhibiting fatty acid synthase would be an effective strategy to treat unresectable hepatic cancer tumor.
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