Is local chemohyperthemia also feasible for metastatic lymph node?

Research Project

Project/Area Number	24701027
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Multi-year Fund
Research Field	Clinical oncology
Research Institution	Ehime University
Principal Investigator	YOSHIDA Motohira 愛媛大学, 医学部附属病院, 講師 (60380218)
Project Period (FY)	2012-04-01 – 2014-03-31
Project Status	Completed (Fiscal Year 2013)
Budget Amount *help	¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000) Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000) Fiscal Year 2012: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Keywords	癌 / 転移リンパ節 / 温熱化学療法
Research Abstract	We have developed docetaxel-embedded magnetoliposome (DML) and reported its feasibility for tumor local chemo-hyperthermia with induction heating. In our report, this treatment have seemed to be effective not only to tumor local but also to metastatic lymph node. We examined whether this treatment was feasible also for metastatic lymph node or not in this study. DMLs were not accumulated in metastatic lymph nodes as our expected, thus, we newly developed micro-bubble liposome. We clarified its effectiveness for more accumulation to metastatic lymph node than DML. We have continued this study using micro-bubble liposome.

Report

(3 results)