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The environment assessment of iron and steel using physiological change of mammalian cells

Research Project

Project/Area Number 24710035
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Environmental impact assessment/Environmental policy
Research InstitutionSuzuka National College of Technology

Principal Investigator

OGAWA Akiko  鈴鹿工業高等専門学校, その他部局等, 講師 (90455139)

Project Period (FY) 2012-04-01 – 2014-03-31
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2013: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2012: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Keywords影響評価手法 / 鉄鋼 / 生体金属
Research Abstract

Essential metals such as zinc and nickel are used for the iron and steel and they may affect on the environment. However, an effective method for evaluating steel has not been established. In this study, we established a simple environmental assessment method for the iron and steel using physiological measurement of mammalian cells. Chinese hamster lung-derived cell, V79, was the most sensitive to concentration change of zinc, nickel and chromium (VI), and V79 was suitable cell for quantitative assessment of the iron and steel. In addition, this method was revealed that corrosion of iron and steel would correlate with the index of proliferation of V79.

Report

(3 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • Research Products

    (20 results)

All 2014 2013 2012 Other

All Journal Article (4 results) (of which Peer Reviewed: 3 results) Presentation (16 results)

  • [Journal Article] Rakkyo fructan as a cryoprotectant for serum-free cryopreservation of mammalian cells2014

    • Author(s)
      Akiko Ogawa, Shinya Mizui, Yasuhito Chida, Masafumi Shimizu, Satoshi Terada, Takeshi Ohura, Kyo-ichi Kobayashi, Saori Yasukawa, Nobuyuki Moriyama
    • Journal Title

      Journal of Bioscience and Bioengineering

      Volume: in press Pages: 1-6

    • NAID

      110009838778

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Cryopreservative solution using rakkyo fructan as cryoprotectant, 23^<rd> European Society for Animal Cell Technology (ESACT) Meeting2013

    • Author(s)
      Satoshi Terada, Shinya Mizui, Yasuhito Chida, Masafumi Shimizu, Akiko Ogawa, Takeshi Ohura, Kyo-ichi Kobayasi, Saori Yasukawa, Nobuyuki Moriyama
    • Journal Title

      Better Cell for Better Health

      Volume: 7巻 Pages: 105-105

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Cryopreservative solution using rakkyo fructan as cryoprotectant2013

    • Author(s)
      Satoshi Terada, Shinya Mizui, Yasuhito Chida, Masafumi Shimizu, Akiko Ogawa, Takeshi Ohura, Kyo-ichi Kobayashi, Saori Yasukawa and Nobuyuki Moriyama
    • Journal Title

      23rd European Society for Animal Cell Technology (ESACT) Meeting: Better Cells for Better Health

      Volume: 7 Pages: 105-105

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Rakkyo fructan as a cryoprotectant for serum-free cryopreservation of mammalian cells

    • Author(s)
      Akiko Ogawa, Shinya Mizui, Yasuhito Chida, Masafumi Shimizu, Satoshi Terada, Takeshi Ohura, Kyo-ichi Kobayashi, Saori Yasukawa, Nobuyuki Moriyama
    • Journal Title

      Journal of Bioscience and Bioengineering

      Volume: (掲載決定)

    • NAID

      110009838778

    • Related Report
      2013 Final Research Report
  • [Presentation] 動物細胞の増殖を指標とした鉄鋼資材の評価方法2014

    • Author(s)
      寺村侑奈、市川美登里、小川亜希子
    • Organizer
      日本鉄鋼協会第167回春季講演大会
    • Place of Presentation
      東京工業大学大岡山キャンパス
    • Related Report
      2013 Final Research Report
  • [Presentation] 鉄鋼存在下での動物細胞(V79)の増殖2014

    • Author(s)
      寺村侑奈、市川美登里、小川亜希子
    • Organizer
      日本鉄鋼協会第167回春季講演大会
    • Place of Presentation
      東京工業大学大岡山キャンパス
    • Related Report
      2013 Final Research Report
  • [Presentation] 亜鉛による細胞増殖抑制と細胞の亜鉛取り込み能との関連2014

    • Author(s)
      小川亜希子、山田悠介、岩田果久
    • Organizer
      第66回日本生物工学会大会(2014)
    • Place of Presentation
      札幌コンベンションセンター
    • Related Report
      2013 Final Research Report
  • [Presentation] 動物細胞の増殖を指標とした鉄鋼資材の評価方法2014

    • Author(s)
      寺村侑奈、市川 美登里、小川 亜希子
    • Organizer
      日本鉄鋼協会第167回春季講演大会
    • Place of Presentation
      東京工業大学大岡山キャンパス(東京都)
    • Related Report
      2013 Annual Research Report
  • [Presentation] 鉄鋼存在下での動物細胞(V79)の増殖2014

    • Author(s)
      寺村侑奈、小川 亜希子
    • Organizer
      日本鉄鋼協会第167回春季講演大会
    • Place of Presentation
      東京工業大学大岡山キャンパス(東京都)
    • Related Report
      2013 Annual Research Report
  • [Presentation] 亜鉛による細胞増殖抑制と細胞の亜鉛取り込み能との関連2014

    • Author(s)
      小川亜希子、山田悠介、岩田果久
    • Organizer
      第66回日本生物工学会大会(2014)
    • Place of Presentation
      札幌コンベンションセンター(北海道)
    • Related Report
      2013 Annual Research Report
  • [Presentation] 金属(Zn、Ni、Cr)イオンが肝細胞の増殖に与える影響2013

    • Author(s)
      丹羽祐太、小川亜希子
    • Organizer
      日本鉄鋼協会第165回春季講演大会
    • Place of Presentation
      東京電機大学
    • Related Report
      2013 Final Research Report
  • [Presentation] Cryopreservative solution using rakkyo fructan as cryoprotectant2013

    • Author(s)
      Satoshi Terada, Shinya Mizui, Yasuhito Chida, Masafumi Shimizu, Akiko Ogawa, Takeshi Ohura, Kyo-ichi Kobayasi, Saori Yasukawa, Nobuyuki Moriyama
    • Organizer
      23^<rd> European Society for Animal Cell Technology (ESACT) Meeting
    • Place of Presentation
      Lille(France)
    • Related Report
      2013 Final Research Report
  • [Presentation] 動物細胞の生理機能変化による亜鉛、ニッケルおよびクロム(VI)の検出への適用と有効金属濃度2013

    • Author(s)
      小川亜希子、兼松秀行、樋尾勝也、玉内秀一
    • Organizer
      日本鉄鋼協会第166回秋季講演大会
    • Place of Presentation
      金沢大学
    • Related Report
      2013 Final Research Report
  • [Presentation] 細胞機能を利用した亜鉛およびニッケル検出法2013

    • Author(s)
      小川亜希子
    • Organizer
      第26回日本動物細胞工学会2013年度大会
    • Place of Presentation
      ホテルフジタ福井
    • Related Report
      2013 Final Research Report
  • [Presentation] Cryopreservative solution using Rakkyo Fructan as Cryoprotectant2013

    • Author(s)
      Satoshi Terada, Shinya Mizui, Yasuhito Chida, Masafumi Shimizu, Akiko Ogawa, Takeshi Ohura, Kyo-ichi Kobayashi, Saori Yasukawa and Nobuyuki Moriyama
    • Organizer
      23rd European Society for Animal Cell Technology (ESACT) Meeting
    • Place of Presentation
      Lille, France
    • Related Report
      2013 Annual Research Report
  • [Presentation] 動物細胞の生理機能変化による亜鉛、ニッケルおよびクロム(VI)の検出への適用と有効金属濃度2013

    • Author(s)
      小川亜希子、兼松秀行、樋尾勝也、玉内秀一
    • Organizer
      日本鉄鋼協会第166回秋季講演大会
    • Place of Presentation
      金沢大学(石川県)
    • Related Report
      2013 Annual Research Report
  • [Presentation] 細胞機能を利用した亜鉛およびニッケル検出法2013

    • Author(s)
      小川亜希子
    • Organizer
      第26回 日本動物細胞工学会2013年度大会 (JAACT2013)
    • Place of Presentation
      ホテルフジタ福井(福井県)
    • Related Report
      2013 Annual Research Report
  • [Presentation] 金属(Zn、Ni、Cr)イオンが肝細胞の増殖に与える影響2013

    • Author(s)
      丹羽祐太、小川亜希子
    • Organizer
      日本鉄鋼協会第165回春季講演大会
    • Place of Presentation
      東京電機大学
    • Related Report
      2012 Research-status Report
  • [Presentation] 動物細胞を利用した鉄鋼材料から調製した溶出液中の亜鉛定量法2012

    • Author(s)
      小川亜希子、樋尾勝也、玉内秀一、兼松秀行
    • Organizer
      日本鉄鋼協会第164回秋季講演大会
    • Place of Presentation
      愛媛大学
    • Year and Date
      2012-09-18
    • Related Report
      2013 Final Research Report 2012 Research-status Report
  • [Presentation] 亜鉛による細胞の形態変化の可視化と亜鉛定量への応用2012

    • Author(s)
      小川亜希子、平井信充、樋尾勝也、玉内秀一、兼松秀行
    • Organizer
      第64回日本生物工学会大会
    • Place of Presentation
      神戸国際会議場
    • Related Report
      2013 Final Research Report 2012 Research-status Report

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Published: 2013-05-31   Modified: 2019-07-29  

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