| Project/Area Number |
24710088
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Environmental technology/Environmental materials
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| Research Institution | Kyushu Institute of Technology |
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Principal Investigator |
KANEKO DAISAKU 九州工業大学, 若手研究者フロンティア研究アカデミー, 准教授 (90467126)
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| Project Period (FY) |
2012-04-01 – 2014-03-31
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2012: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
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| Keywords | ムール貝 / ドーパ / カテコール基 / 原子間力顕微鏡 / 接着剤 / 量子化学計算 / MTT試験 / ALP試験 / ナノ接合 / 植物由来接着剤 / ＡＦＭ / フォースカーブモード / 歯髄細胞 / ＭＴＴ試験 / 国際研究者交流 |
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| Research Abstract |
We set following goals to achieve practical application of our plant-derived adhesives for biomedical fields. 1)To clarify interaction mechanism of catechol group.This research topic was carried out using AFM and we clarified that number of hydroxyl group significantly affect interaction force. We also carried out quantum chemical calculation between catechol group and partially oxidized adherent. It was found that hydroxyl groups of catechol act onto oxygen of adherent and formed strong hydrogen bonding. 2)To clarify bio-affinities of plant-derived adhesives. In this research topic, we used pulpal cell which is the most sensitive cell in human body. We have clarified our plant-derived adhesive never affect even to pulpal cells and their specializations.We concluded monomers of our plant-derived adhesive were adequately selected and synthesized. Our results promise that our plant-derived adhesives can be used in our body everywhere as bio-adhesive.
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