Construction of rigid polymer conjugated oligonucleotide
| Project/Area Number |
24710125
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Nanomaterials/Nanobioscience
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| Research Institution | Suzuka University of Medical Science |
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Principal Investigator |
TASHIRO Ryu 鈴鹿医療科学大学, 薬学部, 助教 (00402785)
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| Project Period (FY) |
2012-04-01 – 2014-03-31
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2012: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
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| Keywords | ＤＮＡデバイス / ナノテクノロジー / DNA / 核酸化学 / 分子デバイス |
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| Research Abstract |
DNA is a powerful tool for creating nanosized architectures and devices owing to its synthetic accessibility and ability to self-assemble. We designed and synthesized a novel H-shaped DNA oligonucleotide dimer cross-linked with a rigid linker. The formation of these motifs was observed via native polyacryla-mide gel analysis and a fluorescence resonance energy transfer experiment using labeled DNA.
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Report
(3 results)
Research Products
(4 results)
