Development of glycan immobilization technique for virus detection and its device applications
Project/Area Number |
24710136
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Multi-year Fund |
Research Field |
Nanomaterials/Nanobioscience
|
Research Institution | Waseda University |
Principal Investigator |
HIDESHIMA SHO 早稲田大学, ナノ理工学研究機構, 講師 (10580433)
|
Project Period (FY) |
2012-04-01 – 2014-03-31
|
Project Status |
Completed (Fiscal Year 2013)
|
Budget Amount *help |
¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
|
Keywords | ナノバイオ / 糖鎖 / バイオセンシング / 電界効果トランジスタバイオセンサ / インフルエンザウイルス / 電界効果トランジスタ / ウイルス |
Research Abstract |
I have developed a glycan immobilization technique for biosensing devices based on filed effect transistors towards influenza virus detection. Highly dense and oriented glycan immobilization has been achieved by introducing an aminooxy-terminated self-assembled monolayer on the sensing surface. The glycan-immobilized FET could detect influenza virus hemagglutinin at attomolar-level sensitivity. The results suggest that the glycan-immobilized FETs developed in the project have potential to detect influenza virus with the high sensitivity.
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Report
(3 results)
Research Products
(16 results)