| Project/Area Number |
24710138
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Microdevices/Nanodevices
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| Research Institution | Tohoku University |
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Principal Investigator |
MIYAKE Takeo 東北大学, 工学(系)研究科(研究院), 助教 (50551529)
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| Project Period (FY) |
2012-04-01 – 2014-03-31
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2013: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Keywords | マイクロ・ナノデバイス / ナノバイオ / バイオインターフェイス / 薬剤投与デバイス / 酵素電池 / ハイドロゲル電極 / ウェットデバイス / イオントフォレシス |
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| Research Abstract |
We report here a transdermal biofuel cell patch that is composed of bioanode fabrics for fructose oxidation, hydrogel tanks containing fructose fuel and chemical compounds (Rhodamine B and ascorbyl glucoside (AG)), O2-diffusion biocathode fabrics, and an ion-isolating hydrophobic flame. When the patch is mounted on the mammalian skin, the patch generate the ionic current of ca.140 microampere cm-2 between the anode and the cathode across the skin. This ion current could be controlled by setting up the external resistance. The applied current induced a water flow of ca. 7.7 microliter cm-2 for 1 h at small current of 5 microampere cm-2 toward the cathode, and then assisted a chemical administration into the skin (ex. AG delivery of 20 microgram cm-2 within the epidermis and 2.5 microgram cm-2 within the dermis) at the anodic side.
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