Development of long-lived luminogenic probes for detection of DNA/RNA in a crude solution
| Project/Area Number |
24710266
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Chemical biology
|
|---|
| Research Institution | Kanagawa University (2013)
The Institute of Physical and Chemical Research (2012) |
|---|
Principal Investigator |
|
|---|
| Project Period (FY) |
2012-04-01 – 2014-03-31
|
| Project Status |
Completed (Fiscal Year 2013)
|
| Budget Amount *help |
¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2012: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
|
|---|
| Keywords | 核酸 / RNA / プローブ / 長寿命発光 / RNA検出 / 夾雑環境 / 長寿命発光発生型プローブ |
|---|
| Research Abstract |
In this study, we developed chemical reaction triggered oligonucleotide probes that could detected DNA/RNA in a crude solution. Our probes have turn-on system that was induced by target DNA/RNA to produce long-lived luminessence. This method applied to the detection of RNA in living bacterial cells.
|
Report
(3 results)
Research Products
(15 results)
-
-
[Journal Article] A Fluorogenic Peptide Probe Developed by In Vitro Selection Using tRNA Carrying a Fluorognic Amino Acid2014
Author(s)
Wei Wang, Takanori Uzawa, Naoya Tochio, Jumpei Hamatsu, Yoshinori Hirano, Seiichi Tada, Hisao Saneyoshi, Takanori Kigawa, Nobuhiro Hayashi, Yutaka Ito, Makoto Taiji, Toshiro Aigaki, Yoshihiro Ito
-
Journal Title
Chem Comm
Volume: 50 (22)
Related Report
Peer Reviewed
-
-
-
-
-
-
-
-
-
-
-
-
-
