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Developmental change of brain function and influence of intervention in childhood.

Research Project

Project/Area Number 24730531
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Educational psychology
Research InstitutionUniversity of Fukui

Principal Investigator

Daisuke Saito  福井大学, 子どものこころの発達研究センター, 特命准教授 (30390701)

Project Period (FY) 2012-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2015: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2013: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
KeywordsfMRI / MRI / Attention Network Test / 発達 / 脳機能 / 脳機能イメージング / 注意機能 / 介入 / 認知機能 / 注意 / 抑制 / 運動
Outline of Final Research Achievements

We investigated brain development from childhood to adulthood using functional magnetic resonance imaging (fMRI) technique. Aim of this study was investigate developmental changes of the attentional ability from a childhood to the adulthood and clarify the intervention that improves its ability.
We estimated the brain function and structure associate with the attentional ability and clarify the age-related changes about brain activity, brain volume and neural network. Furthermore, the correlation of cognitive task performance and hormonal level showed that everyday life environment and a habit were concerned with cognitive function and hormone level, and it became clear to affect the brain function.

Report

(5 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • 2013 Research-status Report
  • 2012 Research-status Report
  • Research Products

    (20 results)

All 2015 2014 2013

All Journal Article (3 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 3 results,  Open Access: 3 results) Presentation (13 results) (of which Int'l Joint Research: 3 results,  Invited: 1 results) Book (4 results)

  • [Journal Article] Autistic empathy toward autistic others2015

    • Author(s)
      Komeda H, Kosaka H, Saito DN, Mano Y, Jung M, Fujii T, Yanaka HT, Munesue T, Ishitobi M, Sato M, Okazawa H
    • Journal Title

      Social cognitive and affective neuroscience

      Volume: 10 (2) Issue: 2 Pages: 145-52

    • DOI

      10.1093/scan/nsu126

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Reduced visual cortex gray matter volume in children and adolescents with reactive attachment disorder.2015

    • Author(s)
      Shimada K, Takiguchi S, Mizushima S, Fujisawa TX, Saito DN, Kosaka H, Okazawa H, Tomoda A.
    • Journal Title

      Neuroimage-Clinical

      Volume: 9 Pages: 13-19

    • DOI

      10.1016/j.nicl.2015.07.001

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Neural basis of psychological growth following adverse experiences: A resting-state functional MRI study.2015

    • Author(s)
      Fujisawa TX, Jung M, Kojima M, Saito DN, Kosaka H, Tomoda A.
    • Journal Title

      PLoS One

      Volume: 10 Issue: 8 Pages: e0136427-e0136427

    • DOI

      10.1371/journal.pone.0136427

    • NAID

      120005756533

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Presentation] 簡易視線追跡装置「GazeFinder®」の思春期・青年期男性における妥当性検証2015

    • Author(s)
      藤岡 徹、岡本 悠子、升谷 泰裕、石飛 信、浅野 みずき、齋藤 大輔、丁 ミンヨン、松村 由紀子、藤澤 隆史、小泉 径子、鈴木 勝昭、土屋 賢治、森 則夫、片山 泰一、棟居 俊夫、友田 明美、小坂 浩隆.
    • Organizer
      第56回日本児童青年精神医学会総会
    • Place of Presentation
      神奈川
    • Year and Date
      2015-09-30
    • Related Report
      2015 Annual Research Report
  • [Presentation] 自閉スペクトラム症特性に関する、Defaolt mode networkの性差2015

    • Author(s)
      水野 賀史、丁 ミンヨン、齋藤 大輔、友田 明美、小坂 浩隆.
    • Organizer
      第56回日本児童青年精神医学会総会
    • Place of Presentation
      神奈川
    • Year and Date
      2015-09-30
    • Related Report
      2015 Annual Research Report
  • [Presentation] Shared right inferior fronto-parietal substrates for corporeal awareness and self-identification.2015

    • Author(s)
      Morita T, Saito DN, Ban M, Shimada K, Okamoto Y, Kosaka H, Okazawa H, Asada M, Naito E.
    • Organizer
      21st Annual Meeting Of The Organization For Human Brain Mapping
    • Place of Presentation
      Hawaii
    • Year and Date
      2015-06-16
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Male brain is more affected by autism spectrum traits than female.2015

    • Author(s)
      Jung M, Saito DN, Tomoda A, Okazawa H, Wada Y, Kosaka H.
    • Organizer
      21st Annual Meeting Of The Organization For Human Brain Mapping
    • Place of Presentation
      Hawaii
    • Year and Date
      2015-06-16
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Association between functional connectivity of default-mode brain and personal growth from adversity.2015

    • Author(s)
      Fujisawa TX, Jung M, Kojima M, Saito DN, Kosaka H, Tomoda A.
    • Organizer
      21st Annual Meeting Of The Organization For Human Brain Mapping
    • Place of Presentation
      Hawaii
    • Year and Date
      2015-06-15
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 発達障害の先端的研究-子どものこころのセンターの取り組み2015

    • Author(s)
      齋藤 大輔
    • Organizer
      第57回日本小児神経学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2015-05-29
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] 自閉症スペクトラム障害(ASD)の安静時脳内ネットワークの特徴2014

    • Author(s)
      丁 ミンヨン、齋藤 大輔、岡本 悠子、藤岡 徹、棟居 俊夫、 友田 明美、岡沢 秀彦、小坂 浩隆
    • Organizer
      第41回日本脳科学会大会
    • Place of Presentation
      福井県県民ホール
    • Year and Date
      2014-11-22 – 2014-11-23
    • Related Report
      2014 Research-status Report
  • [Presentation] 自閉症スペクトラム障害者における扁桃体の安静時脳活動2014

    • Author(s)
      丁 ミンヨン、齋藤 大輔、石飛 信、守田 知代、猪原 敬介、佐々木 章宏、新井 清義、升谷 泰裕、藤岡 徹、岡本 悠子、棟居 俊夫、友田 明美、定藤 規弘、岡沢 秀彦、飯高 哲也、和田 有司、小坂 浩隆
    • Organizer
      第37回日本神経科学大会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2014-09-11 – 2014-09-13
    • Related Report
      2014 Research-status Report
  • [Presentation] Functional connectivity in default mode network predicts autism spectrum traits ?2014

    • Author(s)
      Minyoung Jung, Hirotaka Kosaka, Daisuke N. Saito, Makoto Ishitobi, Tomoyo Morita, Keisuke Inohara, Akihiro Sasaki, Mizuki Asano, Sumiyoshi Arai, Yasuhiro Masuya, Toshio Munesue, Akemi Tomoda, Yuji Wada, Norihiro Sadato, Hidehiko Okazawa, Tetsuya Iidaka
    • Organizer
      Human Brain Mapping
    • Place of Presentation
      CCH-Congress Center in Hamburg, Germany
    • Year and Date
      2014-06-08 – 2014-06-12
    • Related Report
      2014 Research-status Report
  • [Presentation] Developmental changes of attention ability in children and adolescents2014

    • Author(s)
      Daisuke N. Saito, Hisakazu Ymaka, Takeshi Fujii, Hirotaka Kosaka, Noriko Muramatsu, Kyoko Matsumura, Makoto Sato, Hidehiko Okazawa
    • Organizer
      International Workshop on Molecular Functional Imaging for Brain and Gynecologic Oncology
    • Place of Presentation
      ユアーズホテル福井, 福井, Japan
    • Related Report
      2013 Research-status Report
  • [Presentation] fMRI study of the reward system of pediatric patients with Reactive Attachment Disorder2014

    • Author(s)
      Shinichiro Takiguchi, Takeshi X. Fujisawa, Daisuke N. Saito, Chiho Yatsuga, Hirokazu Kumazaki, Sakae Mizushima, Toshiya Aoi, Masahiko Kojima, Hiroaki Naruse, Michiko Koizumi, Minyoung Jung, Hirotaka Kosaka, Akemi Tomoda
    • Organizer
      International Workshop on Molecular Functional Imaging for Brain and Gynecologic Oncology
    • Place of Presentation
      ユアーズホテル福井, 福井, Japan
    • Related Report
      2013 Research-status Report
  • [Presentation] The development of attentional network during childhood and adult: an fMRI study2013

    • Author(s)
      Daisuke N. Saito, Hisakazu Yanaka, Takeshi Fujii, Hirotaka Kosaka, Tomoko Muramatsu, Taisuke Shimada, Kyoko Matsumura, Makoto Sato, Hidehiko Okazawa
    • Organizer
      Human Brain Mapping
    • Place of Presentation
      Seattle, U.S.
    • Related Report
      2013 Research-status Report
  • [Presentation] 注意に関する神経基盤の発達:Voxel-Based Morphometry研究2013

    • Author(s)
      藤井 猛,齋藤 大輔,谷中 久和,小坂 浩隆,村松 倫子,岡沢 秀彦
    • Organizer
      第36回日本神経科学大会
    • Place of Presentation
      国立京都国際会館, 京都, Japan
    • Related Report
      2013 Research-status Report
  • [Book] 発達科学ハンドブック 第8巻『脳の発達科学』2015

    • Author(s)
      齋藤 大輔 共著
    • Total Pages
      317
    • Publisher
      新曜社
    • Related Report
      2015 Annual Research Report
  • [Book] 子どものこころと脳の発達 第5巻1号2014

    • Author(s)
      大阪大学大学院大阪大学・金沢大学・浜松医科大学・千葉大学・福井大学連合小児発達学研究科
    • Total Pages
      72
    • Publisher
      金芳堂
    • Related Report
      2014 Research-status Report
  • [Book] 心の発達の研究最前線:脳科学の観点から-fMRIを中心に2013

    • Author(s)
      滝口 慎一郎, 齋藤 大輔, 小坂 浩隆, 友田 明美
    • Total Pages
      5
    • Publisher
      小児内科
    • Related Report
      2013 Research-status Report
  • [Book] 自閉症スペクトラム障害の社会性障害を探る: fMRI 研究2013

    • Author(s)
      小坂 浩隆, 田邊宏樹, 守田知代, 岡本悠子, 齋藤 大輔, 石飛 信, 棟居 俊夫, 和田 有司, 定藤規弘
    • Total Pages
      6
    • Publisher
      日本生物学的精神医学会誌
    • Related Report
      2013 Research-status Report

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Published: 2013-05-31   Modified: 2019-07-29  

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