| Project/Area Number |
24730563
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Educational psychology
|
|---|
| Research Institution | Institute of Physical and Chemical Research |
|---|
Principal Investigator |
ESPOSITO Gianluca 独立行政法人理化学研究所, 脳科学総合研究センター, 国際特別研究員 (10618341)
|
|---|
| Project Period (FY) |
2012-04-01 – 2014-03-31
|
| Project Status |
Completed (Fiscal Year 2013)
|
| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
|
|---|
| Keywords | Infant carrying / 親子間相互関係 / Infant calming response / Carrying in humans / Maternal carrying / Transport Response / 親子間愛着行動 |
|---|
| Research Abstract |
Mother-infant bonding is the earliest and most critical social relationship of mammalian infants. However, the physiological mechanisms regulating these infant behaviors remain largely undefined. In the current project, we have shown a novel set of infant responses during maternal carrying. Infants under 6 months of age carried by a walking mother immediately stopped voluntary movement and crying and exhibited a rapid heart rate decrease. Furthermore, we identified similar responses in mouse pups. Using pharmacologic and genetic interventions in mouse pups, we identified the neural systems regulating the calming response. The loss of the calming response hindered maternal rescue of the pups, suggesting a functional significance for the identified calming response. Our study has demonstrated for the first time that the infant calming response to maternal carrying is a set of central, motor, and cardiac regulations and is a conserved component of mammalian mother-infant interactions.
|
