Specifiaclly designed treatment strategy for patients with obsessive-compulsive disorder based on symptom dimentions
Project/Area Number |
24730573
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Multi-year Fund |
Research Field |
Clinical psychology
|
Research Institution | Hamamatsu University School of Medicine |
Principal Investigator |
INOUE JUN 浜松医科大学, 医学部附属病院, 臨床心理士 (90535577)
|
Research Collaborator |
SUZUKI Katsuaki 浜松医科大学, 医学部精神医学講座, 准教授
IWATA Yasuhide 浜松医科大学, 医学部附属病院, 講師
MATUO Kayako 浜松医科大学, 医学部精神医学講座, 特任准教授
MOCHIZUKI Yosuke 浜松医科大学, 医学部附属病院, 臨床心理士
|
Project Period (FY) |
2012-04-01 – 2015-03-31
|
Project Status |
Completed (Fiscal Year 2014)
|
Budget Amount *help |
¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2013: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
|
Keywords | 強迫性障害 / 症状ディメンション / 曝露反応妨害法 / 森田療法 / 治療戦略 |
Outline of Final Research Achievements |
We examined clinical records to develop an effective treatment strategy for patients with obsessive-compulsive (OC) symptoms of various dimensions. Our strategy was developed based on our findings that following combinations was effective: the Exposure and Response Prevention therapy for the contamination/washing, the Morita therapy for the aggressive/checking, and other Behavioral techniques and Morita therapy for the symmetry/ordering dimension. The effectiveness of the treatment with the strategy, measured by the Dimensional Yale-Brown Obsessive-Compulsive Scale, was confirmed. fMRI was also performed to assess pre and post-treatment for 4 cases by using a paradigm with pictures evoking OC symptoms. The patients showed alterations in the default mode network (DMN), associated with self-recognition, at the pre-treatment, but the “deactivation” in the DMN was enhanced at the post-treatment. The imaging results indicated the validity of our treatment strategy.
|
Report
(4 results)
Research Products
(10 results)