| Budget Amount *help |
¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2013: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Outline of Final Research Achievements |
In recent years, it has become a social demand to enhance the preparation for hospital discharge of patients with mental disorders. Cognitive remediation therapy (CRT) is developed to improve cognitive abilities that leads to improved social functioning. The study aimed to investigate the effect of CRT on patients with schizophrenia.
The evaluation of cognitive functioning was done using a neuropsychological test, and brain activation was assessed by functional magnetic resonance imaging (fMRI), both before and after the therapy.
First, cognitive function in schizophrenia patients showed an overall decrease in comparison with the normal controls. Second, the neuropsychological test scores after CRT indicated an improvement in memory, attention, and executive functions of schizophrenia patients compared to before the therapy. Third, the results of the examination by fMRI indicated changes in the brain activation levels of schizophrenia patients after the intervention.
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