Role of hydration water on the self-assembly of lipids
Project/Area Number |
24740289
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Multi-year Fund |
Research Field |
Biophysics/Chemical physics
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Research Institution | University of Tsukuba |
Principal Investigator |
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Project Period (FY) |
2012-04-01 – 2015-03-31
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Project Status |
Completed (Fiscal Year 2014)
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Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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Keywords | 水の役割 / 自己組織化 / 脂質膜 / 水和状態 / テラヘルツ分光 / X線小角散乱 / 脂質二重膜 / 自己組織化構造形成 / 水和水 / 水和 / 相転移 / ソフトマター / 生体膜 |
Outline of Final Research Achievements |
For long, water has been considered as just a background medium for the self-assembly of soft matter including biomolecules. However, the present study clarified that structural changes of phospholipid bilayers strongly depends on their hydration states from the measurements of terahertz spectroscopy and small angle-X-ray scattering. Further, ion-dependence of stacking structure of phospholipid membranes revealed that water has some “role” for the interactions between the membranes.
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Report
(4 results)
Research Products
(31 results)
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[Presentation] Stiffening of Lipid bilayer by n-alkane2015
Author(s)
M. Hishida, A. Endo, R. Yanagisawa, K. Nakazawa, Y. Yamamura, K. Saito
Organizer
Physics of Structural and Dynamical Hierarchy in Soft Matter
Place of Presentation
東京大学生産技術研究所
Year and Date
2015-03-16 – 2015-03-18
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