Modeling of cell tissue morphology: Cell adhesion force and cellular arrangement
| Project/Area Number |
24740292
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Biophysics/Chemical physics
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| Research Institution | Tokyo University of Agriculture and Technology (2014)
Kyushu University (2012-2013) |
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Principal Investigator |
YANAGISAWA Miho 東京農工大学, 工学(系)研究科(研究院), 特任准教授 (50555802)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2012: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
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| Keywords | 細胞モデル / 界面張力 / 細胞接着 / 細胞組織モデル / 自己組織化 / ソフトマター / 多細胞モデル / ベシクル / 生体高分子 / 相分離 / 生物物理 / 膜界面 |
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| Outline of Final Research Achievements |
Living cells regulate their shapes and cytoplasmic structures to be appropriate for their functions. To reveal the mechanism to regulate their shapes and structures, we used adhering droplets entrapping a polymer blend as a model of cellular tissue, and investigated relation between adhesion force between the cells and cellular arrangement. Consequently, it is found that the adhesive force and the cellular arrangement have a codependent relationship via structural formation of the polymer blend in cells.
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Report
(4 results)
Research Products
(35 results)
