Study for synthesis of organic molecules based on chiral organometallic catalysts containing C,N-polydentate ligands
| Project/Area Number |
24750084
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Synthetic chemistry
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| Research Institution | Nagoya University |
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Principal Investigator |
ITO Jun-ichi 名古屋大学, 工学(系)研究科(研究院), 講師 (20402480)
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| Project Period (FY) |
2012-04-01 – 2014-03-31
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2012: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
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| Keywords | 不斉金属触媒 / 多座配位子 / ピンサー型錯体 / オキサゾリン配位子 / カルベン配位子 / 触媒反応 / 有機金属錯体 / 不斉反応 / C-H結合切断 / C-C結合生成 / ロジウム / ルテニウム / イリジウム |
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| Research Abstract |
In this study, we elucidated the development of new transition metal catalyst containing carbon-nitrogen based chiral polydentate ligands. As a result, we have successfully synthesized new polydentate ligands containing oxazoline and N-heterocyclic carbene fragments and their transition metal complexes having rhodium, iridium, cobalt and ruthenium. In those catalysts, we developed several types of asymmetric transformations, namely asymmetric conjugate reduction of a,b-unsaturated carbonyl compounds, direct asymmetric alkynylation of aldehydes. In addition, we also found that pincer type iridium complexes exhibited C-H activation reaction of benzene derivatives and they served as a catalyst on bolylation reaction of aromatic compounds. Furthermore, the iridium complex was successfully applied to C-H activation of unactivated alkanes, giving the corresponding alkyl complexes.
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Report
(3 results)
Research Products
(22 results)
