Creation of novel controlled drug release material using surface cationic poly(N-vinylamide) gel
| Project/Area Number |
24750220
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Polymer/Textile materials
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| Research Institution | Osaka University |
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Principal Investigator |
AJIRO Hiroharu 大阪大学, 臨床医工学融合研究教育センター, 特任准教授(常勤) (50437331)
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| Project Period (FY) |
2012-04-01 – 2014-03-31
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2013: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2012: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Keywords | 薬物徐放 / ゲル / 薬物伝達システム |
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| Research Abstract |
Novel materials for controlled drug release system have been investigated using poly(N-vinylamide), which can be cationized only on surface. sPIC gel (surface polyion complex gel) was introduced with interpenetrating polymer network, using vinyl phosphonic acid, and its drug releasing control was examined. Poly(ethylene glycol) was introduced into poly(N-vinylacetamide) gel to obtain the high mechanical strength. Chitosan as cationic polymer was employed for hydrogel to absorb electrostatically charged drugs.
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Report
(3 results)
Research Products
(47 results)
