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Application of the atmospheric plasma surface treatment for allogenic bone grafting: Safety improvement and enhanced bone healing.

Research Project

Project/Area Number 24760029
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Thin film/Surface and interfacial physical properties
Research InstitutionShimane University

Principal Investigator

IMADE Shinji  島根大学, 医学部, 助教 (10581077)

Project Period (FY) 2012-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Fiscal Year 2013: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Keywordsプラズマ表面処理 / 同種骨移植 / 高温加圧滅菌 / 大気圧下プラズマ表面処理 / 骨癒合促進 / 骨癒合能 / 国際情報交換
Outline of Final Research Achievements

We evaluated the bone healing property of the autoclaved allogenic bone compared with the low-temperature sterilized allogenic bone quantitatively, and investigated the effect of the plasma surface treatment on it.
In conclusion, the bone healing capability of the autoclaved allogenic bone was decreased by 25% compared with the low-temperature sterilized allogenic bone. Oxygen plasma treatment of 1 minute may have a positive effect on bone healing of the autoclaved allogenic bone, but this phenomenon was not reproducible. We believe that the study of the plasma surface treatment for bone healing should be continued.

Report

(4 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • 2012 Research-status Report
  • Research Products

    (1 results)

All 2012

All Presentation (1 results)

  • [Presentation] 骨釘に対するオートクレーブ滅菌の有用性:オートクレーブ滅菌とガス滅菌の比較2012

    • Author(s)
      今出真司、内尾祐司
    • Organizer
      日本整形外科学会基礎学術集会
    • Place of Presentation
      名古屋国際会議場(名古屋市)
    • Related Report
      2012 Research-status Report

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Published: 2013-05-31   Modified: 2019-07-29  

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