| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2012: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
|
|---|
| Research Abstract |
Protein adsorbed film on joint prosthesis material affecting tribological property was evaluated by using electrochemical method. Albumin and gamma-globurin contained in natural cynovial fluid was selected for measurement. The combination of ultra-high molecular weight polyethylene (GUR1050) and CoCrMo alloy (ASTMF75) was employed. The potential between CoCrMo alloy and protein solution was measured to understand the behaviour of protein adsorption. Albumin was easily peeled off by shear force, it means the adsorption is weak. Gamma-globulin did not show desorption by shear force. Therefore, the difference of adsorption strength and stability is essence to form protein adsorption film.
|
