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Development of bio-optical imaging microscope using supercontinuum (SC) light source

Research Project

Project/Area Number 24760320
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Measurement engineering
Research InstitutionUniversity of the Ryukyus

Principal Investigator

MIYAGI Kazuya  琉球大学, 工学部, 助教 (50512688)

Project Period (FY) 2012-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2014: ¥130,000 (Direct Cost: ¥100,000、Indirect Cost: ¥30,000)
Fiscal Year 2013: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2012: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Keywords波長分散 / 非線形光学効果 / 自己位相変調法 / スーパーコンティニューム光 / フォトニック結晶ファイバ / 生体顕微鏡 / 有限要素法
Outline of Final Research Achievements

Bio-imaging (i.e. observation of cells, biological tissue) tools has become essential in life science research by advancing medical and engineering cooperation by technological innovation. Low-invasive medical technique by using establishment of stabilizing operation of broadband light source has attracted much attention from recent years. In this research, we verify the possibility of fluorescence microscope using Supercontinuum (SC) light source, thereby we can indicate effectiveness of fluorescence microscope using SC light source by comparing suggested method (i.e. SC light-fluorescence microscope) and two types (using halogen lamp and metal halide lamp) conventional fluorescence microscope. Therefore, suggested method was able to clearly confirm the brightness of the fluorescence of living cells.

Report

(4 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • 2012 Research-status Report
  • Research Products

    (7 results)

All 2014 2013

All Journal Article (2 results) (of which Peer Reviewed: 2 results) Presentation (5 results)

  • [Journal Article] Dynamic Control of Mode Field Diameter and Effective Area by Germanium Doping of Hexagonal Photonic Crystal Fibers2013

    • Author(s)
      Kazuya Miyagi, Yoshinori Namihira, Yuho Kasamatsu, and Anwar Hossain
    • Journal Title

      Optical Review

      Volume: 20 Pages: 327-331

    • NAID

      10031187934

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Dynamic Control of Mode Field Diameter and Effective Area by Germanium Doping of Hexagonal Photonic Crystal Fiber2013

    • Author(s)
      Kazuya Miyagi, Yoshinori Namihira, Yuho Kasamatsu and Md.Anwar Hossain
    • Journal Title

      Optical review

      Volume: 未定

    • NAID

      10031187934

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Presentation] フォトニック結晶ファイバの材料-構造特性と非線形屈折率(n2)における相関特性の検討2014

    • Author(s)
      宮城加津也,西川諒,安里真太郎,二宮諒
    • Organizer
      電気学会九州支部沖縄支所講演会
    • Place of Presentation
      沖縄県,西原町,琉球大学
    • Year and Date
      2014-11-29
    • Related Report
      2014 Annual Research Report
  • [Presentation] 六角形Ge添加コアフォトニック結晶ファイバを用いた波長分散制御及び分散マネジメントへの検討2014

    • Author(s)
      西川諒,安里真太郎,二宮諒,宮城加津也
    • Organizer
      電気学会九州支部沖縄支所講演会
    • Place of Presentation
      沖縄県,西原町,琉球大学
    • Year and Date
      2014-11-29
    • Related Report
      2014 Annual Research Report
  • [Presentation] FFS法を用いた各種フォトニック結晶ファイバのk-factorに関する検討2014

    • Author(s)
      安里真太郎,二宮諒,西川諒,宮城加津也
    • Organizer
      電気学会九州支部沖縄支所講演会
    • Place of Presentation
      沖縄県,西原町,琉球大学
    • Year and Date
      2014-11-29
    • Related Report
      2014 Annual Research Report
  • [Presentation] スーパーコンティニューム光源による蛍光顕微鏡を用いた乳がん細胞の画像イメージングへの検討2014

    • Author(s)
      二宮諒,安里真太郎,西川諒,宮城加津也
    • Organizer
      電気学会九州支部沖縄支所講演会
    • Place of Presentation
      沖縄県,西原町,琉球大学
    • Year and Date
      2014-11-29
    • Related Report
      2014 Annual Research Report
  • [Presentation] Dynamic Control of Effective Area and nonlinearity by changing Ge-doped rate for photonic crystal fibers2013

    • Author(s)
      Kazuya Miyagi, Yoshinori Namihira, Khoyu Nohara, and Ryo Nishikawa
    • Organizer
      The 2013 international conference on advanced technologies for communications
    • Place of Presentation
      ホーチミンシティー(ベトナム)
    • Related Report
      2013 Research-status Report

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Published: 2013-05-31   Modified: 2019-07-29  

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