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Fabrication of biosensor for specific pollutant detection based on the biological magnetic particle synthesis

Research Project

Project/Area Number 24760646
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Biofunction/Bioprocess
Research InstitutionTokyo University of Agriculture and Technology

Principal Investigator

TANAKA Masayoshi  東京農工大学, 工学(系)研究科(研究院), 助教 (60533958)

Project Period (FY) 2012-04-01 – 2014-03-31
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2012: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Keywords磁性細菌 / 磁気微粒子 / 環境モニタリング / 重金属 / バイオセンサ / マグネタイト / 磁気計測
Research Abstract

In this research project, to develop a magnetic biosensor for specific pollutant detection, magnetotactic bacteria was investigated, because of their activity of magnetic particle production. Here we evaluated minimum inhibitory concentration (MIC) and magnetite productivity profiles of the magnetotactic bacteria grown in the presence of various transition metal ions and metalloid oxyanion. As a result, the highest doping of Co, Mn and Cu in bacterial magnetite were successfully found and the MIC profiles were also metal ion dependents. In addition, magnetic measurements of these bacteria grown in different condition revealed the difference of the magnetic property. Based on these information, a prototype of microbial biosensor system has been fabricated. Using the results and information in this study, novel biosensing system for highly specific detection of pollutant will be developed in near future.

Report

(3 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • Research Products

    (3 results)

All 2014 2012

All Journal Article (2 results) (of which Peer Reviewed: 2 results) Presentation (1 results)

  • [Journal Article] Highest levels of Cu, Mn and Co doped into nanomagnetic magnetosomes through optimized biomineralisation2012

    • Author(s)
      Tanaka, M., Brown, R., Hondow, N., Arakaki, A., Matsunaga, T. and Staniland, S.
    • Journal Title

      J. Mater. Chem

      Volume: Vol.22 (24) Issue: 24 Pages: 11919-11919

    • DOI

      10.1039/c2jm31520c

    • Related Report
      2013 Final Research Report 2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Fabrication of Lipid Tubules with Embedded Quantum Dots by Membrane Tubulation Protein2012

    • Author(s)
      Masayoshi Tanaka
    • Journal Title

      SMALL

      Volume: 8 Issue: 10 Pages: 1590-1595

    • DOI

      10.1002/smll.201102446

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Presentation] 二次元フォトセンサを利用した広視野細胞蛍光イメージングシステムの開発2014

    • Author(s)
      菅村百合子、佐伯達也、細川正人、田中祐圭、林泰圭、原田学、松永是、田中剛
    • Organizer
      電気化学会
    • Place of Presentation
      関西大学千里山キャンパス
    • Year and Date
      2014-03-29
    • Related Report
      2013 Annual Research Report 2013 Final Research Report

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Published: 2013-05-31   Modified: 2019-07-29  

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