Elucidation of RNA metabolism regulation important for plant cell totipotency
| Project/Area Number |
24770052
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Plant molecular biology/Plant physiology
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| Research Institution | Nara Institute of Science and Technology (2014)
Institute of Physical and Chemical Research (2012-2013) |
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Principal Investigator |
OHTANI Misato 奈良先端科学技術大学院大学, バイオサイエンス研究科, 助教 (60435633)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2013: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2012: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | 分化全能性 / RNA代謝 / プレｍRNAスプライシング / RNA品質管理 / snRNA / シュート再生 / 脱分化 / 器官再生 / pre-mRNAスプライシング / 国際情報交換 |
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| Outline of Final Research Achievements |
The cell potentiality to give rise to a whole body is called “totipotency”, and plant somatic cells are considered to retain this ability. In this project, molecular genetics works were performed with Arabidopsis thaliana mutants, to reveal molecular mechanisms underlying plant cell totipotency, especially from the viewpoint of RNA metabolism regulation. The obtained results suggested that specific RNA metabolism regulatory pathways, such as pre-mRNA splicing regulation and/or RNA quality control mechanism, have critical roles in plant cell totipotency.
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Report
(4 results)
Research Products
(26 results)
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[Journal Article] Multiple classes of transcription factors regulate the expression of VASCULAR-RELATED NAC-DOMAIN7, a master switch of xylem vessel differentiation2015
Author(s)
Endo H, Yamaguchi M, Tamura T, Nakano Y, Nishikubo N, Yoneda A, Kato K, Kubo M, Kajita S, Katayama Y, Ohtani M, Demura T
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Journal Title
Plant and Cell Physiology
Volume: 56
Issue: 2
Pages: 242-254
DOI
Related Report
Peer Reviewed / Open Access
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