analyses of splicing-dependent stress response mechanism
| Project/Area Number |
24770166
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Molecular biology
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| Research Institution | Kyoto University |
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Principal Investigator |
NINOMIYA Kensuke 京都大学, 医学(系)研究科(研究院), 助教 (00437279)
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| Project Period (FY) |
2012-04-01 – 2014-03-31
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2012: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
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| Keywords | 遺伝子発現制御 / ストレス応答 / スプライシング / RNA |
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| Research Abstract |
We have found a novel mechanism of splicing-dependent regulation of gene expression, attributing to certain stress recovery function of cells. Thus, we analyzed its molecular mechanism and found some candidates for trans-acting proteins required for this splicing-dependent regulation. In addition, we searched for other genes regulated by this novel mechanism and obtained a number of candidate genes.
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Report
(3 results)
Research Products
(3 results)
