Zooanthroponoses and Great Ape-specific diseases

• Project/Area Number: 24770234
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Physical anthropology
• Research Institution: Rakuno Gakuen University
• Principal Investigator: KOORIYAMA Takanori 酪農学園大学, 獣医学群, 准教授 (50416278)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Project Status: Completed (Fiscal Year 2014)
• Budget Amount: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000); Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
• Keywords: 人獣共通感染症 / チンパンジー / 寄生虫 / ウイルス / 細菌 / 野生 / 糞中抗体 / 野生動物保護 / マハレ山塊国立公園 / ヘルペスウイルス / 百日咳 / ﾊﾟﾗｲﾝﾌﾙｴﾝｻﾞｳｲﾙｽ / タンザニア / 糞中IgA / EBウイルス / サイトメガロウイルス / パラインフルエンザウイルス / 血清診断 / 病原体遺伝子検査

Outline of Final Research Achievements

We performed serological examinations using coprologic antibodies in the Mahale Mountains National Park, Tanzania, to determine if chimpanzees were infected with zooanthroponotic diseases. After two field surveys, we found no clinical signs of infection. Based on parasitological surveys, chimpanzees were not infected with human-borne pathogenic parasites, but were infected with nematodes, cestodes, and protozoa, as has been previously demonstrated. We detected antibodies against Epstein-Barr virus, Cytomegalovirus, Varicella-zoster virus, Bordetella pertussis, and Parainfluenza virus 1/2/3 based on faecal antibody analysis. Human Herpes virus 6 DNA was detected in total DNA extracted from chimpanzee faeces. Overall, our results elucidate the infection history of human-borne zoonotic pathogens in wild chimpanzees in Mahale. Antibody detection based on faecal samples is a useful tool for revealing infectious disease through non-invasive sampling.

Research Products

• [Journal Article] 研究紹介 人と動物の関係・人間活動と動物生態の関係 (2013)
  • Author(s): 郡山 尚紀
  • Journal Title: 北海道獣医師会誌 Volume: 57 Pages: 25-32
• [Journal Article] 外国文化に親しむ－私たちの国はこんな所－(8) 【タンザニア連合共和国】観光地開発と野生動物保全のはざまに立つタンザニア (2013)
  • Author(s): 郡山尚紀
  • Journal Title: 酪農ジャーナル Volume: 66 Pages: 44-45
• [Journal Article] Epidemiological study of zoonoses derived from humans in captive chimpanzees. (2013)
  • Author(s): Kooriyama T, Okamoto M, Yoshida T, Nishida T, Tsubota T, Saito A, Tomonaga M, Matsuzawa T, Akari H, Nishimura H, Miyabe-Nishiwaki T.
  • Journal Title: Primates Volume: 54 Issue: 1 Pages: 89-98
  • DOI: 10.1007/s10329-012-0320-8
  • NAID: 10031147951
  • Peer Reviewed
• [Presentation] 野生チンパンジーと飼育下チンパンジーのヒト由来病原体への暴露に関する血清学 的研究 (2014)
  • Author(s): 郡山尚紀・伊藤葉子
  • Organizer: 野生動物と社会
  • Place of Presentation: 愛知県犬山市
  • Year and Date: 2014-11-01 – 2014-11-03
• [Book] Mahale Chimpanzees 50 Years of Research (2015)
  • Author(s): MICHIO NAKAMURA, KAZUHIKO HOSAKA, NORIKO ITOH, KOICHIRO ZAMMA
  • Total Pages: 782
  • Publisher: Cambridge University Press
• [Remarks] 酪農学園大学獣医学群獣医保健看護学類動物行動学ユニット
  • URL: http://rgufd.rakuno.ac.jp/search/index.html