| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Outline of Final Research Achievements |
We performed serological examinations using coprologic antibodies in the Mahale Mountains National Park, Tanzania, to determine if chimpanzees were infected with zooanthroponotic diseases. After two field surveys, we found no clinical signs of infection. Based on parasitological surveys, chimpanzees were not infected with human-borne pathogenic parasites, but were infected with nematodes, cestodes, and protozoa, as has been previously demonstrated. We detected antibodies against Epstein-Barr virus, Cytomegalovirus, Varicella-zoster virus, Bordetella pertussis, and Parainfluenza virus 1/2/3 based on faecal antibody analysis. Human Herpes virus 6 DNA was detected in total DNA extracted from chimpanzee faeces. Overall, our results elucidate the infection history of human-borne zoonotic pathogens in wild chimpanzees in Mahale. Antibody detection based on faecal samples is a useful tool for revealing infectious disease through non-invasive sampling.
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