Syntheses and applications of jasmonate analogs

• Project/Area Number: 24780107
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Bioproduction chemistry/Bioorganic chemistry
• Research Institution: Hirosaki University
• Principal Investigator: TAKADA NOBORU 弘前大学, 農学生命科学部, 准教授 (10332701)
• Project Period (FY): 2012-04-01 – 2016-03-31
• Project Status: Completed (Fiscal Year 2015)
• Budget Amount: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000); Fiscal Year 2015: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2014: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2013: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
• Keywords: ジャスモン酸ミミック / 化学合成 / 構造活性相関 / 構造活性相関研究 / 光学分割 / 抽だい

Outline of Final Research Achievements

Jasmonate is one of plant hormones and is involved in various processes. In this study, we aimed to develop a bolting inhibitor based on structure-activity relationship studies of jasmonates. Methyl 3-iso-cucurbate was found to inhibit the stem elongation (bolting) of Brassica plants. Furthermore, its application did not induce leaf senescence. Therefore, it is a potential bolting inhibitor for winter annual crops.

Research Products

• [Journal Article] Ophiobolides, Polyketides Isolated from Ophiobolus sp. KTC 2293 (2016)
  • Author(s): Tayone, W. C.; Tanaka, K.; Takada, N.
  • Journal Title: Chiang Mai. J. Sci. Volume: 43 Issue: 13 Pages: 476-482
  • DOI: 10.1021/jo00065a011
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Achaetolide-II isolated from Helminthosporium velutinum TS28 (2015)
  • Author(s): M Arayama, H Maeda, K Tanaka, N Takada, T Nehira, M Hashimoto
  • Journal Title: Tetrahedron Volume: 71(41) Issue: 41 Pages: 7900-7905
  • DOI: 10.1016/j.tet.2015.08.013
  • Peer Reviewed / Open Access
• [Journal Article] Methyl 3-iso-cucurbate, a potential bolting inhibitor to Brassica rapa. (2013)
  • Author(s): Takada, N.; Wakita, E.; Yamazaki, E.; Hashimoto, M.; Koda, Y.
  • Journal Title: Tetrahedron Volume: 69 Issue: 26 Pages: 5426-5430
  • DOI: 10.1016/j.tet.2013.04.107
  • Peer Reviewed
• [Journal Article] Isolation and Identification of Causal Constituents of Green Discoloration in Garlic Puree. (2012)
  • Author(s): Yamazaki, Y.; Takada, N.; Okuno, T.
  • Journal Title: Food Sci. Technol. Res. Volume: 18 Pages: 673-678
  • NAID: 10031054552
  • Peer Reviewed
• [Presentation] イモグサレセンチュウ被害から学ぶ新しい線虫対策への試み
  • Author(s): 高田 晃
  • Organizer: 第20回スパイス＆ハーブ研究成果セミナー
  • Place of Presentation: 山崎香辛料振興財団
  • Invited
• [Presentation] Natural Plant Products Controlling Crop Developments
  • Author(s): Takada, N.
  • Organizer: 特別講義
  • Place of Presentation: Davao Oriental State College of Science and Technology