Epidemiological investigation on antimicrobial resistance, especially beta-lactam resistance, in Enterobacteriaceae isolated from companion animals
Project/Area Number |
24780299
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Multi-year Fund |
Research Field |
Applied veterinary science
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Research Institution | Tottori University |
Principal Investigator |
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Project Period (FY) |
2012-04-01 – 2016-03-31
|
Project Status |
Completed (Fiscal Year 2015)
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Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2015: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2013: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2012: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
|
Keywords | 薬剤耐性菌 / 伴侶動物 / グラム陰性桿菌 / 微生物 / 獣医学 / 基質拡張型β-ラクタマーゼ / 院内伝播 / 犬 / 腸内細菌 / セファロスポリナーゼ / インテグロン / フルオロキノロン耐性 |
Outline of Final Research Achievements |
In this study, I investigated prevalence of antimicrobial resistance and its epidemiological characteristics in various Gram-negative bacteria isolated from companion animals. Resistance to the tested antimicrobials were less prevalent in Proteus mirabilis and Acinetobacter spp. In contrast, resistances to antimicrobials including beta-lactams were highly prevalent in Klebsiella spp. and Enterobacter spp. isolated from dogs and cats. Most of beta-lactam-resistant isolates in these bacteria had extended-spectrum beta-lactamases. These findings suggest that prevalence of antimicrobial resistance can differ by bacterial species. Notably, Klebsiella spp. and Enterobacter spp. are regarded as important antimicrobial-resistant bacteria in veterinary medicine and public health.
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Report
(5 results)
Research Products
(10 results)