The research for highly pathogenic porcine reproductive and respiratory syndrome virus.
Project/Area Number |
24780301
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Multi-year Fund |
Research Field |
Applied veterinary science
|
Research Institution | National Agriculture and Food Research Organization |
Principal Investigator |
ISEKI Hiroshi 独立行政法人農業・食品産業技術総合研究機構, 動物衛生研究所 ウイルス・疫学研究領域, 主任研究員 (90548207)
|
Project Period (FY) |
2012-04-01 – 2015-03-31
|
Project Status |
Completed (Fiscal Year 2014)
|
Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2014: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2013: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
|
Keywords | 豚 / ウイルス / PRRS / 遺伝子 / 診断 / 繁殖 / 呼吸器 / 流産 |
Outline of Final Research Achievements |
Although the highly pathogenic porcine reproductive and respiratory syndrome virus (HP-PRRSV) has not yet been detected in Japan, we must operate under the assumption that the virus could eventually spread there. Through this research issue, we successfully developed a genetic diagnostic method detecting for HP-PRRSV RNA and typical (non-highly pathogenic) PRRSV RNA, respectively. The animal experiment using HP-PRRSV was first report in our country, thus we can provide the insights into their pathogenicity and the property of viral load of HP-PRRSV. Moreover, we clarify the immune response to the Japanese isolate was able to strongly alleviate subsequent manifestation of HP-PRRS. However, this also means that recognition of HP-PRRSV invasion in Japan may be difficult, as symptoms will not be obvious.
|
Report
(4 results)
Research Products
(5 results)