| Project/Area Number |
24780303
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Applied veterinary science
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| Research Institution | National Institute of Infectious Diseases |
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Principal Investigator |
YOSHIKAWA Tomoki 国立感染症研究所, ウイルス第一部, 研究員 (20399463)
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| Project Period (FY) |
2012-04-01 – 2014-03-31
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2013: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Fiscal Year 2012: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | イヌジステンパーウイルス / ウイルス / 犬ジステンパー / リバースジェネティクス |
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| Research Abstract |
There was a canine distemper outbreak, which is generally known to be occurred in carnivore happened in the monkey colony in an animal quarantine. Hence to understand the pathogenesis, the sequences from the in vitro isolates and from these of clinical specimens were determined and analyzed by utilizing next-generation sequencing technique. In addition, establishment of the reverse genetics system based on the S-CDV sequence, which enable to produce the infectious particles from the plasmids were tried.
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