Evaluation for the prognostic index of SIRS and a target for blood purification therapy in dogs

Research Project

Project/Area Number	24780310
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Multi-year Fund
Research Field	Clinical veterinary science
Research Institution	Yamaguchi University (2013) Kagoshima University (2012)
Principal Investigator	SHIMOKAWA Takako 山口大学, 獣医学部, 助教 (50594404)
Project Period (FY)	2012-04-01 – 2014-03-31
Project Status	Completed (Fiscal Year 2013)
Budget Amount *help	¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000) Fiscal Year 2013: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000) Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Keywords	SIRS / プロカルシトニン / HMGB1 / 敗血症
Research Abstract	To investigate the possibility of procalcitonin as a prognostic index of SIRS and a target for blood purification therapy in dogs, a measuring system for canine procalcitonin using ELISA has been established. A recombinant canine procalcitonin protein and polyclonal antibodies were obtained by cloning canine procalcitonin gene cDNA. These antibodies specifically recognized canine procalcitonin and was able to detect canine procalcitonin by ELISA.

Report

(3 results)