Development of quality evaluation method of licorice by metabolomics
| Project/Area Number |
24790125
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Environmental pharmacy
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| Research Institution | Osaka University |
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Principal Investigator |
HARADA Kazuo 大阪大学, 薬学研究科(研究院), 助教 (50397741)
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| Project Period (FY) |
2012-04-01 – 2014-03-31
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2012: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
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| Keywords | 薬用資源学 / メタボローム / カンゾウ / 生薬 / 甘草 / 品質評価 |
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| Research Abstract |
Quality evaluation and control of herbal medicines are important but difficult issues. Licorice is the one of the most important herb in Japan, and regulated by glycyrrhizine content according to Pharmacopeia of Japan. However, biological activities of licorice extracts, such as suppression of nitric oxide generation in macrophase cell, could not be estimated by just only glycyrrhizine content of licorice. However, those could be estimated by metabolome data which possesses comprehensive component data accurately. We suggested that metabolome data in harbal extract is quite useful for quality evaluation of herbal medicines.
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Report
(3 results)
Research Products
(9 results)
