| Project/Area Number |
24790152
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Medical pharmacy
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| Research Institution | Osaka University |
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Principal Investigator |
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| Project Period (FY) |
2012-04-01 – 2014-03-31
|
| Project Status |
Completed (Fiscal Year 2013)
|
| Budget Amount *help |
¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
|
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| Keywords | 職業性曝露 / 抗がん剤 / LC-MS/MS / 多成分同時分析 / エアサンプリング |
|---|
| Research Abstract |
In this research, multicomponent high-performance liquid chromatography/tandem mass spectrometry analysis of ten chemotherapeutic drugs was newly developed and validated, and was adapted to two different types of external exposure studies. In addition, evaluable system of drug volatilities was newly developed, and intended to further internal exposure studies, simultaneous quantification of unchanged and metabolized drug was developed.
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