| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2012: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
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| Research Abstract |
To identify the novel miRNA markers for arteriosclerosis, we first screened total RNA samples derived from patient's plasma using a microarray platform. As a result, several circulating miRNAs were identified to be differentially expressed. We also demonstrated that optimal RNA extraction method of miRNA from human plasma samples for quantitative PCR. These results suggest that circulating miRNAs are available as a novel biomarker to assess the arteriosclerosis.
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