Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2013: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2012: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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Research Abstract |
We clarified the protective effect of hypotaurine on TR-TBT18d-1 cells, rat placental cell line, exposed with oxidative stress. This study suggested that anti-hydroxyradical and -peroxyradical effects were involved in the protective effect of hypotaurine. Interestingly, the expression of rodent Slc6a13, which is a GABA transporter and express in peripheral organs such as placenta, was contributed to the protection against the oxidative stress and apoptosis induced by hydrogen peroxide.
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