| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2013: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
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| Outline of Final Research Achievements |
I analyzed the autophagy in the regeneration and the formation of the skeletal muscle. By the experiment of the regeneration, expression of LC3 increased after the damage of the skeletal muscle immediately and LC3 formed a small vesicle. Autophagosome was few in a myoblasts at the time of the skeletal muscle formation, but autophagosome was increased after differentiation, and autophagosome were become autolysosome when myoblasts differentiated into myotubes. These results suggested that the autophagy played an important role in the regeneration and the formation of the skeletal muscle.
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