Analyses of human embryos using three-dimensional imaging and DNA extraction
| Project/Area Number |
24790195
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
General anatomy (including Histology/Embryology)
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| Research Institution | Kyoto University |
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Principal Investigator |
SHIGHEHITO Yamada 京都大学, 医学(系)研究科(研究院), 教授 (80432384)
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| Research Collaborator |
IMAI Hirohiko
MAKISHIMA Haruyuki
TAKAKUWA Tetsuya
YONEYAMA AKio
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2013: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | 解剖学 / 発生学 / 画像解剖学 / Ｘ線イメージング / MRI / X線イメージング / ヒト胚子 / 画像診断 / 先天異常学・奇形学 |
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| Outline of Final Research Achievements |
The human embryos samples derived from the Kyoto Collection of Human Embryos were imaged in several imaging modalities such as phase-contrast X-ray computed tomography (PXCT) and magnetic resonance microscopy (MRM). Fine images were obtained by human embryos ranging from Carnegie stage (CS) 13 to 23, and by human fetuses in early fetal period before 22 weeks of gestation. Epidemiological data associated with the human embryos and fetuses were digitized, and genetic information from old samples preserved in formalin solution for several decades were also extracted. Using these results, a new type of database was expected including morphological, epidemiological and genetic data to elucidate the mechanism of normal development and pathogenesis of congenital anomalies in humans.
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Report
(4 results)
Research Products
(71 results)
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[Presentation] Fetal pituitary hyperintensity on T1-weighted images: Appearance in less than 21 weeks gestational age fetuses.2014
Author(s)
Mehemed TM, Fushimi Y, Okada T, Yamamoto A, Kanagaki M, Okada T, Sakamoto R, Takakuwa T, Yamada S, Togashi K
Organizer
International Congress of Radiology ICR2014
Place of Presentation
Dubai, UAE
Year and Date
2014-09-09 – 2014-09-12
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[Presentation] 口蓋帆挙筋の神経支配についての考察2014
Author(s)
岸本英明、山田重人、益岡 弘 河合勝也、鈴木茂彦
Organizer
第38回日本口蓋裂学会総会・学術集会
Place of Presentation
札幌コンベンションセンター、 札幌市
Year and Date
2014-05-29 – 2014-05-30
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[Presentation] 胎生初期の低栄養環境が仔ラットの骨成長に及ぼす影響2013
Author(s)
木村 智子, 玉川 俊広, 金子 隼也, 原澤 俊也, 河野 匡暁, 野津 瑛未奈, 森田 航, 中務 真人, 山田 重人, 宇田川 潤, 工藤 基
Organizer
第118回日本解剖学会学術集会
Place of Presentation
高松
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