A study of the mechanisms involved in the atmospheric pressure change detection
Project/Area Number |
24790239
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Multi-year Fund |
Research Field |
Environmental physiology (including Physical medicine and Nutritional physiology)
|
Research Institution | Keio University |
Principal Investigator |
MEGUMI Funakubo 慶應義塾大学, 医学部, 講師(非常勤) (90548538)
|
Project Period (FY) |
2012-04-01 – 2015-03-31
|
Project Status |
Completed (Fiscal Year 2014)
|
Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2014: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2013: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2012: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
|
Keywords | 気圧 / 内耳 / 痛み / 三叉神経 / TRPV |
Outline of Final Research Achievements |
I previously reported that distinct neurons in the vestibular nucleus as well as trigeminal nucleus caudalis responded to lowering barometric pressure by electrophysiological study. I aim to examine whether the vestibular nucleus neurons of conscious rats are affected by lowering barometric pressure(LP). C-Fos expression was examined in the vestibular nucleus by immunohistochemistry. In LP groups, the number of c-Fos immunoreactive neurons showed a significant increase compared to control groups. The data imply that lowering barometric pressure could affect the vestibular system.
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Report
(4 results)
Research Products
(1 results)