Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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Outline of Final Research Achievements |
We investigated several stem-like phenotype markers in follicular lymphoma patient samples, and some minor population was positive for these stem-like markers. These cells harbored t(14;18) by microdissection study. Furthermore, some minor stem-like positive cells presented in human derived B-cell lymphoma cell lines and these minor populations had treatment resistance and strong tumorigenic potential by in vitro and in vivo assay.
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