Xenophagy membrane dynamics
Project/Area Number |
24790413
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Multi-year Fund |
Research Field |
Bacteriology (including Mycology)
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Research Institution | Tokyo Medical and Dental University |
Principal Investigator |
NOZAWA Takashi 東京医科歯科大学, 医歯(薬)学総合研究科, 助教 (10598858)
|
Project Period (FY) |
2012-04-01 – 2014-03-31
|
Project Status |
Completed (Fiscal Year 2013)
|
Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2013: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2012: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
|
Keywords | オートファジー / A群レンサ球菌 / Rabタンパク質 / Rab GTPase |
Research Abstract |
We could identify newly 4 Rab GTPases as an autophagy regulator during bacteial infection. These Rab proteins were not involved in starvation-induced autophagy, suggesting these regulators are responsible for autophagic membrane dynamics for bacteria.
|
Report
(3 results)
Research Products
(28 results)
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[Journal Article] Development of two-step multiple PCR assay for typing of capsular polysaccharide synthesis gene clusters of Streptococcus suis2014
Author(s)
M. Okura, C. Lachance, M. Osaki, T. Sekizaki, F. Maruyamam, T. Nozawa, Nakagawa, S. Hamada, C. Rossignol, M. Gottschalk, D. Takamatsu
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Journal Title
J. Clin. Microbiol
Volume: 52
Pages: 1714-9
Related Report
Peer Reviewed
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[Journal Article] Development of a two-step multiplex PCR assay for typing of capsular polysaccharide synthesis gene clusters of Streptococcus suis2014
Author(s)
Okura M, Lachance C, Osaki M, Sekizaki T, Maruyama F, Nozawa T, Nakagawa I, Hamada S, Rossignol C, Gottschalk M, Takamatsu D
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Journal Title
J Clin Microbiol
Volume: 52
Issue: 5
Pages: 1714-1719
DOI
Related Report
Peer Reviewed / Open Access
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[Journal Article] Endogenous nitrated nucleotide is a key mediator of autophagy and innate defense against bacteria.2013
Author(s)
Ito C, Saito Y, Nozawa T, Fujii S, Sawa T, Inoue H, Matsunaga T, Khan S, Akashi S, Hashimoto R, Aikawa C, Takahashi E, Sagara H, Komatsu M, Tanaka K, Akaike T, Nakagawa I, Arimoto H.
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Journal Title
Mol. Cell
Volume: 52
Issue: 6
Pages: 794-804
DOI
Related Report
Peer Reviewed / Open Access
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