Research Project
Grant-in-Aid for Young Scientists (B)
It is well known that some co-localized proteins with amyloid fibrils, which are called amyloid associated proteins, may play important roles in amyloidosis. Then, we tried to pick up the strong candidates as early diagnostic markers and/or therapeutic molecules of amyloidosis in this study. As the results of our studies, we could detect some strong candidates, such as clusterin and vitronectin. Serum clusterin levels of familial amyloidotic polyneuropathy (FAP) patients was significantly higher than that of healthy volunteers. Moreover, significant higher correlation between vitronectin and TTR deposition was observed in the cardiac tissues of FAP patients.
All 2014 2013 2012
All Journal Article (27 results) (of which Peer Reviewed: 24 results, Open Access: 1 results) Presentation (17 results)
J Immunol
Volume: (in press)
Cell Metab
Volume: 19 Pages: 712-21
Stem Cell Res
Volume: 12 Pages: 574-83
臨床病理
Volume: 62 Pages: 291-6
Volume: 12 Issue: 2 Pages: 574-83
10.1016/j.scr.2014.01.004
Cell Metab.
Volume: 9 Issue: 4 Pages: 712-721
10.1016/j.cmet.2014.03.006
Amyloid
Volume: 20 Pages: 251-5
Int J Cardiol
Volume: 170 Pages: 69-74
J Neurol Neurosurg Psychiatry
Muscle Nerve
Volume: 48 Pages: 839-841
Volume: 20 Pages: 142-150
Clin Chim Acta
Volume: 419 Pages: 127-131
Volume: 170 Issue: 1 Pages: 69-74
10.1016/j.ijcard.2013.10.033
Volume: 20 Issue: 4 Pages: 251-255
10.3109/13506129.2013.844122
Volume: - Issue: 7 Pages: 740-746
10.1136/jnnp-2013-305973
Volume: 48(5) Issue: 5 Pages: 839-41
10.1002/mus.23939
Volume: 20(3) Issue: 3 Pages: 142-50
10.3109/13506129.2013.797890
Volume: 419 Pages: 127-31
10.1016/j.cca.2013.02.002
FEBS Lett
Volume: 586 Pages: 4215-4222
Pancreas
Volume: 41 Pages: 971-973
Lab Invest
Volume: 92 Pages: 474-484
Volume: 19 Pages: 50-2
FEBS Letters
Volume: 586 Issue: 23 Pages: 4215-4222
10.1016/j.febslet.2012.10.025
Volume: 41 Issue: 6 Pages: 971-973
10.1097/mpa.0b013e318249926a
Volume: 92 Issue: 3 Pages: 474-84
10.1038/labinvest.2011.195
Volume: 19 (Suppl 1) Issue: sup1 Pages: 50-2
10.3109/13506129.2012.674988
Volume: 19 Suppl 1 Issue: sup1 Pages: 45-46
10.3109/13506129.2012.674075