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Evaluation of Clinical Usefulness of a Local Arterial Wall Elasticity by an Ultrasonic Phased-Tracking Method

Research Project

Project/Area Number 24790561
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Laboratory medicine
Research InstitutionJichi Medical University

Principal Investigator

OGATA YUKIYO  自治医科大学, 医学部, 講師 (10448847)

Project Period (FY) 2012-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2012: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywords頸動脈 / 弾性率 / プラーク / 位相差トラッキング / 位相差トラッキング法 / 位相差トラッキング方法 / 頸動脈超音波検査 / 頸動脈プラーク / 高血圧症
Outline of Final Research Achievements

We made a measurement system of the carotid arterial wall elasticity using an ultrasonic phased-tracking method. It involved in a series of the work concerned with the analysis of the images. First, we compared the elasticity distribution image with pathological image. It clarified the problem that there is a restriction of the frame-rate for keeping the accuracy of analysis of the elasticity distribution at a high level. Second, we evaluated the availability of the carotid arterial wall elasticity by phased-tracking method in hypertension patients. The patients whose IMT was thicker and had much plaque had worse elasticity. And patients whose the value of the elasticity was higher had faster pulse wave velocity. Moreover, the intake of salt and the aortic brood pressure showed positive correlations with the elasticity. The elasticity was higher in the patients had cardiovascular event. However, no significant difference was found between that group and event free group.

Report

(6 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • 2013 Research-status Report
  • 2012 Research-status Report
  • Research Products

    (1 results)

All 2012

All Journal Article (1 results)

  • [Journal Article] 早期動脈硬化における血管機能検査の現状と新たな展開2012

    • Author(s)
      小形幸代、谷口信行
    • Journal Title

      日本臨床検査医学会

      Volume: 60巻 Pages: 887-894

    • NAID

      10031123909

    • Related Report
      2012 Research-status Report

URL: 

Published: 2013-05-31   Modified: 2019-07-29  

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