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Analysis of trace elements in deciduous enamel of children to retrospectively evaluate the prenatal environment

Research Project

Project/Area Number 24790592
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Hygiene
Research InstitutionJuntendo University

Principal Investigator

MATSUKAWA Takehisa  順天堂大学, 医学部, 助教 (60453586)

Project Period (FY) 2012-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2013: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Keywords微量元素 / 乳歯 / 出生前エナメル / LA-ICP-MS / レーザーアブレーション / 誘導結合プラズマ質量分析 / ICP-MS
Outline of Final Research Achievements

After Fukushima nuclear power plant accident, it has raised the need to determine the quantities of radionuclides in order to assess their potential impact on public health. A mass spectrometry is used for the determination of many long-lived radionuclides with low specific activities in biological samples. Human tooth enamel provides a nearly permanent and chronological record of an individual’s environmental exposure during development. We have conducted to make procedure for analysis of elemental distribution in deciduous enamel of children to retrospectively evaluate the prenatal radionuclides exposure. We demonstrates the validity of laser ablation-inductively coupled plasma-mass spectrometry (LA-ICP-MS) to provide elemental distribution information in dental tissues for Fukushima’s children.

Report

(4 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • 2012 Research-status Report
  • Research Products

    (8 results)

All 2015 2014 2013 2012

All Journal Article (2 results) Presentation (6 results) (of which Invited: 1 results)

  • [Journal Article] 微量元素の胎児期曝露による小児発達障害への影響に関する研究2013

    • Author(s)
      横山和仁, 篠原光代, 松川岳久, 西岡笑子
    • Journal Title

      平成24年度順天堂ハイテク・リサーチセンター 環境医学研究所紀要

      Volume: 7 Pages: 46-48

    • Related Report
      2013 Research-status Report
  • [Journal Article] 微量元素の胎児期曝露指標 乳歯エナメル質中の微量元素分析法の開発2013

    • Author(s)
      松川岳久, 向山翔, 平田岳史, 横山和仁
    • Journal Title

      産業衛生学雑誌

      Volume: 55 Pages: 39-39

    • Related Report
      2013 Research-status Report
  • [Presentation] 福島に住む児童の乳歯エナメル質を用いた胎児期環境評価の基礎検討2015

    • Author(s)
      松川岳久、横山和仁、平田岳史、林英男、篠原厚子、千葉百子、大森由紀、篠原光代、権 章武
    • Organizer
      第85回日本衛生学会学術総会
    • Place of Presentation
      和歌山
    • Year and Date
      2015-03-26 – 2015-03-28
    • Related Report
      2014 Annual Research Report
  • [Presentation] 乳歯エナメル質を用いた胎児期有害元素曝露評価法の開発2014

    • Author(s)
      松川岳久, 横山和仁, 平田岳史, 林秀男, 篠原厚子, 千葉百子, 大森由紀
    • Organizer
      第84回日本衛生学会学術総会
    • Place of Presentation
      岡山
    • Year and Date
      2014-05-25 – 2014-05-27
    • Related Report
      2014 Annual Research Report
  • [Presentation] レーザーアブレーション-ICP質量分析法(LA-ICPMS法)の生体応用2013

    • Author(s)
      平田岳史, 向山翔, 坂田周平, 岡林識起, 篠原厚子, 松川岳久,横山和仁
    • Organizer
      プラズマ分析研究会第87回講演会
    • Place of Presentation
      東京
    • Related Report
      2012 Research-status Report
  • [Presentation] 小児の毛髪中微量元素濃度とその情動・認知行動への影響2013

    • Author(s)
      松川岳久, 横山和仁
    • Organizer
      第118回 日本解剖学会総会
    • Place of Presentation
      高松
    • Related Report
      2012 Research-status Report
    • Invited
  • [Presentation] 乳歯エナメル質を用いた胎児期の内部被曝評価法の開発2012

    • Author(s)
      松川岳久, 向山翔, 平田岳史,横山和仁
    • Organizer
      第77回日本民族衛生学会総会
    • Place of Presentation
      東京
    • Related Report
      2012 Research-status Report
  • [Presentation] 微量元素の胎児期曝露指標 -乳歯エナメル質中の微量元素分析法の開発-2012

    • Author(s)
      松川岳久, 向山翔, 平田岳史,横山和仁
    • Organizer
      第24回産業神経・行動学研究会
    • Place of Presentation
      東京
    • Related Report
      2012 Research-status Report

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Published: 2013-05-31   Modified: 2019-07-29  

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