Development of hybrid screening system for barrier-disrupted and immune-activated substance
| Project/Area Number |
24790596
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Hygiene
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| Research Institution | Setsunan University |
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Principal Investigator |
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| Project Period (FY) |
2012-04-01 – 2014-03-31
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| Project Status |
Completed (Fiscal Year 2013)
|
| Budget Amount *help |
¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2013: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Keywords | アレルギー応答 / 腸管バリア / バリア機能 |
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| Research Abstract |
It is suggested that the immune diseases such as allergies causes it with the disruption of epithelial cell barrier. In this study, we performed the basic data for development of the hybrid detection system that could evaluate the barrier function and the immune response by an environmental pollution at the same time. It was observed that various environmental pollutants were decreased barrier function, and disrupted the immune response. There results suggest the possibility to develop the hybrid detection system that could evaluate the barrier function and the immune response by an environmental pollution at the same time.
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Report
(3 results)
Research Products
(19 results)
