Predictors and prognostic impact of post-traumatic stress disorder after the great East Japan earthquake in patients with cardiovascular disease.

• Project/Area Number: 24790605
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Public health/Health science
• Research Institution: Tohoku University
• Principal Investigator: Nochioka Kotaro 東北大学, 大学病院, 助教 (20598411)
• Project Period (FY): 2012-04-01 – 2016-03-31
• Project Status: Completed (Fiscal Year 2015)
• Budget Amount: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000); Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
• Keywords: 東日本大震災 / 心血管疾患 / 予後 / 外傷後心的ストレス障害 / 危険因子 / PTSD / 心不全 / 死亡 / 精神的ストレス / 心的外傷後ストレス障害・反応 / 心的外傷後ストレス障害

Outline of Final Research Achievements

BACKGROUND: We examined the prevalence, predictors and prognostic impact of post-traumatic stress disorder (PTSD) after the Great East Japan Earthquake in patients with cardiovascular disease (CVD) in the CHART-2 study.
METHODS and RESULTS: The prevalence of PTSD was 14.7% after the Earthquake. Female sex, experiencing the Tsunami, property loss, poverty, and insomnia medication use were associated with PTSD. The patients with PTSD more frequently experienced a composite of death, acute myocardial infarction, stroke and heart failure (18.5% vs. 15.0%, P=0.035).
CONCLUSIONS: PTSD was frequent in CVD patients after the Earthquake and had an adverse prognostic impact.

Research Products

• [Journal Article] Predictors and Prognostic Impact of Post-Traumatic Stress Disorder After the Great East Japan Earthquake in Patients With Cardiovascular Disease (2015)
  • Author(s): Takeo Onose, Kotaro Nochioka, Yasuhiko Sakata, Masanobu Miura, Soichiro Tadaki, Ryoichi Ushigome, Takeshi Yamauchi, Kenjiro Sato, Kanako Tsuji, Ruri Abe, Satoshi Miyata, Jun Takahashi, Hiroaki Shimokawa, on behalf of the CHART-2 Investigators
  • Journal Title: Circulation Journal Volume: 79 Issue: 3 Pages: 664-667
  • DOI: 10.1253/circj.CJ-14-1403
  • NAID: 130004927110
  • ISSN: 1346-9843, 1347-4820
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Presentation] Lessons from the Great East Japan Earthquake Disaster. (2016)
  • Author(s): 青木竜男
  • Organizer: 第80回 日本循環器学会学術集会
  • Place of Presentation: 仙台国際センター（仙台市）
  • Year and Date: 2016-03-18
  • Int'l Joint Research
• [Presentation] Longitudinal study of post-traumatic stress disorder after the Great East Japan Earthquake Disaster in cardiovascular disease patients -The CHART Study- (2013)
  • Author(s): 後岡広太郎
  • Organizer: 第17回日本心不全学会学術集会
  • Place of Presentation: 大宮
• [Presentation] Psychological Impact of the Great East Japan Earthquake in Patients with Cardiovascular Diseases -A Report from the CHART-2 Study-
  • Author(s): Kotaro Nochioka, Yasuhiko Sakata, Satoshi Miyata, Masanobu Miura, Tsuyoshi Takada, Jun Takahashi,
  • Organizer: 第77回日本循環器学会学術集会
  • Place of Presentation: 横浜
• [Presentation] Psychological Impact of the Fukushima Daiichi Nuclear Accident in Patients with Cardiovascular Diseases
  • Author(s): Kotaro Nochioka, Yasuhiko Sakata, Satoshi Miyata,
  • Organizer: 第77回日本循環器学会学術集会
  • Place of Presentation: 横浜
• [Remarks] HEART 東北大学病院 循環器内科広報誌（第40号）
  • URL: http://www.cardio.med.tohoku.ac.jp/class/heart/pdf/heart40.pdf