Dementia in Nepal, surveys onelderly and their family including social and environmental factors for the comparative study with Japan

• Project/Area Number: 24790610
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Public health/Health science
• Research Institution: Fukushima Medical University (2013-2014); Yamagata University (2012)
• Principal Investigator: ISEKI Chifumi 福島県立医科大学, 公私立大学の部局等, 助教 (80436211)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Project Status: Completed (Fiscal Year 2014)
• Budget Amount: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000); Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2012: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
• Keywords: gerontology / dementia / Nepal / developing country / comparative study / cognitive function / social factors / ネパール / 発展途上国 / 認知症 / 国際比較 / 高齢者 / 家族 / 認知機能低下 / 疫学 / 文化人類学 / 南アジア / 地域在住住民 / 国際情報交換 / 社会医学 / 文化

Outline of Final Research Achievements

To reveal the prevalence of dementia and the associated factors of dementia, we interviewed about 130 elderly people over 60 years of age and their families in Nepal.
The concept of dementia was not common among them and the elderly in Nepal tended to score lower in cognitive examinations than elderly Japanese. The prevalence of dementia above 60 years of age was 10% which seemed to be affected by limited years of education and gender. The attitude of the families of older people in relation to their cognitive changes was receptive and optimistic and they did not regard dementia as a problem.
We also interviewed 20 medical workers in Nepal to guage their awareness of dementia and end-of-life care. This revealed that there was a difference of understanding in the concept of dementia between those in rural areas and in the capital city and there was little association between medical care and end-of-life for people in Nepal.

Research Products

• [Journal Article] Incidence of idiopathic normal pressure hydrocephalus (iNPH): a 10-year follow-up study of a rural community in Japan. (2014)
  • Author(s): Iseki C, Takahashi Y, Wada M, Kawanami T, Adachi M, Kato T
  • Journal Title: J Neurol Sci Volume: 339 Issue: 1-2 Pages: 108-112
  • DOI: 10.1016/j.jns.2014.01.033
  • Peer Reviewed / Open Access
• [Journal Article] Chronic Headache and Sleepiness Caused by Facial Soap (Containing Hydrolyzed Wheat Protein)-Induced Wheat Allergy: A Case Report (2014)
  • Author(s): Iseki C, Kawanami T, Tsunoda T, Chinuki Y, Kato T
  • Journal Title: Intern Med Volume: 53 Pages: 151-154
  • Peer Reviewed
• [Journal Article] Acupuncture Alleviated the Nonmotor Symptoms of Parkinson’s Disease including Pain, Depression, and Autonomic Symptoms (2014)
  • Author(s): C Iseki, T Furuta, M Suzuki, S Koyama, K Suzuki, T Suzuki, A Kaneko, T Mitsuma
  • Journal Title: Case Reports in Neurological Medicine Volume: 2014 Pages: 953109-953109
  • DOI: 10.1155/2014/953109
  • Peer Reviewed / Open Access
• [Journal Article] ネパールにおける高齢者と認知症 (2014)
  • Author(s): 伊関千書，公平瑠奈，幅崎麻紀子，高橋賛美，Basant Pant，加藤丈夫
  • Journal Title: Journal International Health Volume: 29 Pages: 59-67
  • NAID: 130004471903
  • Peer Reviewed
• [Journal Article] ネパールにおける高齢者と認知症 (2014)
  • Author(s): 伊関千書 公平瑠奈 幅崎麻紀子 高橋賛美 Basant Pant 加藤丈夫
  • Journal Title: Journal of International Health Volume: 未定
  • NAID: 130004471903
  • Peer Reviewed
• [Journal Article] Chronic Headache and Sleepiness Caused by Facial Soap (Containing Hydrolyzed Wheat Protein)-Induced Wheat Allergy: A Case Report. (2013)
  • Author(s): Chifumi Iseki, Toru Kawanami, Takahiko Tsunoda, Yuko Chinuki,Takeo Kato
  • Journal Title: Journal of Internal Medicine Volume: 53 Pages: 151-154
  • Peer Reviewed
• [Journal Article] 多様な課題が含まれる「宿題帳」を継続することで農村地域住民の語の流暢性が向上した―自治体主催の介護予防事業の有用性と評価法の検討. (2013)
  • Author(s): 伊関千書 高橋賛美 和田学 川並透 鈴木匡子 加藤丈夫
  • Journal Title: Dementia Japan Volume: 27 Pages: 62-69
  • Peer Reviewed
• [Journal Article] 地域住民のうつ予防 (2013)
  • Author(s): 伊関千書 加藤丈夫
  • Journal Title: 神経内科 Volume: 79 Pages: 129-134
• [Journal Article] 多様な課題が含まれる「宿題帳」を継続することで農村地域住民の語の流暢性が向上した―自治体主催の介護予防事業の有用性と評価法の検討 (2013)
  • Author(s): 伊関千書, 高橋賛美, 和田学, 川並透, 加藤丈夫
  • Journal Title: Dementia Japan Volume: 27 Pages: 62-69
  • Peer Reviewed
• [Journal Article] The Subclinical Decline in Verbal Fluency and Motor Regulation Associated with AVIM (Asymptomatic Ventriculomegaly with Features of Idiopathic NPH on MRI). A Case-control Study (2013)
  • Author(s): Iseki C, Takahashi Y, Wada M, Kawanami T, Kato T
  • Journal Title: Intern Med Volume: 52
  • Peer Reviewed
• [Journal Article] Changes in subarachnooid space precede ventriculomegaly in idiopathic normal pressure hydrocephalus (2012)
  • Author(s): Iseki C, Takahashi Y, Wada M, Arawaka S, Kawanami T, Kato T
  • Journal Title: Intern Med Volume: 51
  • Peer Reviewed
• [Journal Article] Carpal tunnel syndrome as an initial manifestation in a case of transthyretin-related familial amyloid polyneuropathy with a novel A120T mutation (2012)
  • Author(s): Koyama S, Kawanami T, Kurokawa K, Tanji H, Iseki C, Arawaka S, Wada M, Kato T
  • Journal Title: Clin Neurol Neurosurg Volume: 114 Issue: 6 Pages: 707-709
  • DOI: 10.1016/j.clineuro.2011.11.030
  • Peer Reviewed
• [Journal Article] Reversible distension of the subarachnoid space around the optic nerves in a case of idiopathic hypertrophic pachymeningitis (2012)
  • Author(s): Hiraka T, Koyama S, Kurokawa K, Tanji H, Iseki C, Wada M, Kawanami T, Oda A, Hosoya T, Kato T
  • Journal Title: Magn Reson Med Sci Volume: 11 Pages: 41-44
  • NAID: 10030799968
  • Peer Reviewed
• [Journal Article] 長期間経過を観察し得た腓腹筋肥大を伴うS1神経根症の１症例 (2012)
  • Author(s): 伊関千書, 丹治治子, 和田学, 川並透, 加藤丈夫
  • Journal Title: 神経内科 Volume: 77 Pages: 417-419
  • Peer Reviewed
• [Presentation] 介護老人福祉・保健施設における終末期看取り体制の構築と医療-介護連携 ～山形県Ｑ地域において (2015)
  • Author(s): 野崎俊介、伊関千書、加藤丈夫
  • Organizer: 第56回日本神経学会学術大会
  • Place of Presentation: 新潟
  • Year and Date: 2015-05-22
• [Presentation] 地域在住高齢者における特発性正常圧水頭症の罹患率 (2014)
  • Author(s): 高橋賛美, 伊関千書, 公平瑠奈, 佐藤秀則, 佐藤裕康, 小山信吾，荒若繁樹, 和田学，川並透, 加藤丈夫
  • Organizer: 第33回日本認知症学会学術集会
  • Place of Presentation: 神奈川
  • Year and Date: 2014-11-29 – 2014-12-01
• [Presentation] 難治性疼痛に対して烏頭剤と鍼灸治療が奏功した線維筋痛症の1例
  • Author(s): 1. 伊関千書 鈴木雅雄 鈴木朋子 金子明代 古田大河 佐橋佳郎 三潴忠道
  • Organizer: 日本東洋医学会東北支部会
  • Place of Presentation: 山形市
• [Presentation] 難治性疼痛に対して烏頭剤と鍼灸治療が奏功した線維筋痛症の1例
  • Author(s): 1. 伊関千書 鈴木雅雄 鈴木朋子 金子明代 古田大河 佐橋佳郎 三潴忠道
  • Organizer: 福島医学会
  • Place of Presentation: 福島市
• [Presentation] Dynamic Serum Concentration of Alkaloids in Pharmaco-therapeutic usage of Aconitum: A case report.
  • Author(s): 12. Chifumi Iseki, Yuji Fujita, Yoshiro Sahashi, Tomoko Suzuki, Akiyo Kaneko, Tadamichi Mitsuma
  • Organizer: Asia Pacipic Association of Medical Toxicology 12th International Scientific Congress
  • Place of Presentation: Dubai
• [Presentation] The incidence of idiopathic normal pressure hydrocephalus (iNPH) in Japanese elderly: A longitudinal, community-based study for 10 years.
  • Author(s): Iseki C, Takahashi Y, Koyama S, Arawaka S, Wada M, Kawanami T, Kato T
  • Organizer: The 4th Meeting of International Society for Hydrocephalus and Cerebrospinal Fluid Disorders
  • Place of Presentation: Westin Miyako Hotel, Kyoto, Japan
• [Presentation] 地域コホートからのiNPHの発症―山形県高畠町の70歳から80歳までの縦断研究より
  • Author(s): 伊関千書 高橋賛美 小山信吾 荒若繁樹 和田学 川並透 加藤丈夫
  • Organizer: 第53回日本神経学会総会
  • Place of Presentation: 東京国際フォーラム、東京
• [Presentation] Non-DESH type iNPH に関する検討 山形県高畠町のコホートから
  • Author(s): 伊関千書 高橋賛美 川並透 加藤丈夫
  • Organizer: 第14回日本正常圧水頭症学会
  • Place of Presentation: 東京ステーションコンファランス、東京
• [Book] 「症例で学ぶ高次脳機能障害―病巣部位からのアプローチ」正常圧水頭症 (2014)
  • Author(s): 伊関千書, 鈴木匡子
  • Total Pages: 274
  • Publisher: 中外医学社