| Project/Area Number |
24790615
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Public health/Health science
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| Research Institution | Osaka University (2013-2014)
Mie University (2012) |
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Principal Investigator |
YAMADA Tomomi 大阪大学, 医学(系)研究科(研究院), 寄附講座准教授 (60363371)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2013: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2012: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Keywords | ミネラル / アトピー性皮膚炎 / PIXE分析 / 測定誤差 / 個人内分散 / TES法 / SIMEX法 / PIXE / ロジスティックモデル |
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| Outline of Final Research Achievements |
In 2005, we started a cohort study following 834 mother-infant pairs who were participating in both the national one-month and ten-month health checkups in Fukuoka City. The objective was to determine the association between atopic dermatitis (AD) and 32 identified hair minerals measured by proton induced X-ray emission (PIXE) method. Mineral amounts together with individual AD family history were incorporated into a logistic model to predict the risk of infant AD. In 2011, six years after initial research, we sampled 209 then 6 year-old children from the original cohort to more extensively statistically analyze their hair mineral amounts for intra-individual variations as well as to confirm associations between hair minerals and AD. As a result we succeeded in creating a statistical technique correcting for measurement errors of hair minerals.
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