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The effects of amino acid intakes on intelligence and cognitive function. - A large-scale longitudinal study in the community-dwelling middle-aged and elderly-

Research Project

Project/Area Number 24790634
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Public health/Health science
Research InstitutionNational Center for Geriatrics and Gerontology

Principal Investigator

KATO Yuki  独立行政法人国立長寿医療研究センター, NILS-LSA活用研究室, 研究員 (20329650)

Co-Investigator(Renkei-kenkyūsha) SHIMOKATA Hiroshi  名古屋学芸大学, 大学院栄養科学研究科, 教授 (10226269)
ANDO Fujiko  愛知淑徳大学, 健康医療科学部, 教授 (90333393)
OTSUKA Rei  独立行政法人国立長寿医療研究センター, NILS-LSA活用研究室, 室長 (00532243)
IMAI Tomoko  同志社女子大学, 生活科学部, 教授 (20329650)
Project Period (FY) 2012-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Keywords知能 / アミノ酸摂取量 / 食事秤量記録調査 / 地域在住中高年者 / 認知機能 / 動物性プロリン / 長期縦断疫学研究 / 動物性食品由来アミノ酸 / 中高年者 / 3日間の食事秤量記録調査
Outline of Final Research Achievements

The aim of this study was to elucidate the effect of amino acid intake on age-related changes in intelligence among Japanese middle-aged and elderly.
First, we constructed the Amino Acid Composition Table of Food containing amino acid compositions in 1,745 food items. In the examination about the effect of the proline intake to the age-related changes of the “Information” scores over a 10-years, as for the middle-aged men and women, the high intake group of proline derived from animal food was significantly increased, compared to the low intake group. Also, the elderly women in the high proline intake group maintained their scores higher than others in the low proline intake group. On the other hand, no significant relationship was observed between the plant-derived proline intake and the “Information” score. Animal-derived proline intake may have some benefit on maintaining age-related changes in intelligence among the middle-aged and elderly.

Report

(4 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • 2012 Research-status Report
  • Research Products

    (10 results)

All 2014 2013 2012 Other

All Journal Article (2 results) (of which Peer Reviewed: 2 results) Presentation (3 results) Remarks (5 results)

  • [Journal Article] 地域在住中高年者のプロリン摂取量が知能に及ぼす影響に関する長期縦断疫学研究2014

    • Author(s)
      加藤友紀,大塚 礼,西田裕紀子,丹下智香子,今井具子,安藤富士子,下方浩史
    • Journal Title

      日本未病システム学会雑誌

      Volume: 20 (1) Pages: 99-104

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] 地域在住中高年者のアミノ酸摂取量-食品アミノ酸成分表の新規構築による推定-2013

    • Author(s)
      加藤友紀,大塚 礼,今井具子,安藤富士子,下方浩史
    • Journal Title

      栄養学雑誌

      Volume: 71(6) Pages: 299-310

    • NAID

      130004735308

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Presentation] 地域在住中高年者の性・年代別たんぱく質摂取量の推移2014

    • Author(s)
      加藤友紀,大塚礼,今井具子,安藤富士子,下方浩史
    • Organizer
      第24回日本疫学会学術総会
    • Place of Presentation
      仙台
    • Related Report
      2013 Research-status Report
  • [Presentation] 地域在住中高年者のプロリン摂取量が知能に及ぼす影響に関する縦断的研究2013

    • Author(s)
      加藤友紀,大塚礼,西田裕紀子,丹下智香子,今井具子,安藤富士子,下方浩史
    • Organizer
      第20回日本未病システム学会学術総会
    • Place of Presentation
      東京
    • Related Report
      2013 Research-status Report
  • [Presentation] 地域在住中高年者のアミノ酸摂取量に関する疫学研究2012

    • Author(s)
      加藤友紀、大塚 礼、今井具子、安藤富士子、下方浩史
    • Organizer
      第59回日本栄養改善学会
    • Place of Presentation
      名古屋
    • Related Report
      2012 Research-status Report
  • [Remarks] NILS-LSA活用研究室ホームページ

    • URL

      http://www.ncgg.go.jp/department/ep/index-j.html

    • Related Report
      2014 Annual Research Report
  • [Remarks] NILS食品アミノ酸成分表2010のダウンロードサイト

    • URL

      http://www.ncgg.go.jp/department/ep/amino.html

    • Related Report
      2014 Annual Research Report
  • [Remarks] NILS-LSA活用研究室ホームページ

    • URL

      http://www.ncgg.go.jp/department/ep/index-j.html

    • Related Report
      2013 Research-status Report
  • [Remarks] 「NILS食品アミノ酸成分表2010」のダウンロードサイト

    • URL

      http://www.ncgg.go.jp/department/ep/amino.html

    • Related Report
      2013 Research-status Report
  • [Remarks] NILS-LSA活用研究室ホームページ

    • URL

      http://www.ncgg.go.jp/department/ep/index-j.html

    • Related Report
      2012 Research-status Report

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Published: 2013-05-31   Modified: 2019-07-29  

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